摘要
目的探讨左氧氟沙星联合奥美拉唑治疗消化性溃疡的临床疗效。方法选取50例消化性溃疡患者,采用随机数字表法分为对照组和研究组,每组25例。对照组患者采用常规(口服左氧氟沙星片)治疗,研究组患者在对照组基础上联用奥美拉唑肠溶胶囊治疗。比较两组患者临床治疗效果、治疗过程中不良反应发生率及治疗前后幽门螺杆菌清除情况。结果治疗后,研究组治疗总有效率(96%)明显高于对照组(68%),差异具有统计学意义(P<0.05)。研究组幽门螺杆菌清除率(92%)显著低于对照组(60%),差异具有统计学意义(P<0.05)。研究组不良反应发生率(20%)低于对照组(56%),差异具有统计学意义(P<0.05)。结论左氧氟沙星联合奥美拉唑治疗消化性溃疡的临床疗效显著,安全性良好,值得临床推广使用。
Objective To explore the clinical efficacy of levofloxacin combined with omeprazole on peptic ulcer.Methods 50 patients with peptic ulcer were selected and divided into a control group and a study group by random number table method,with 25 cases in each group.The control group was treated with conventional therapy(oral levofloxacin tablets),and the study group was treated with omeprazole enteric capsules on the basis of the control group.The clinical therapeutic effect,the incidence of adverse reactions during treatment and the clearance of Helicobacter pylori before and after treatment were compared between the two groups.Results After treatment,the total effective rate of the study group(96%)was significantly higher than the control group(68%),and the difference was statistically significant(P<0.05).The Helicobacter pylori clearance rate in the study group(92%)was significantly lower than the control group(60%),and the difference was statistically significant(P<0.05).The incidence of adverse reactions in study group(20%)was lower than the control group(56%),and the difference was statistically significant(P<0.05).Conclusion Levofloxacin combined with omeprazole is effective and safe in the treatment of peptic ulcer,and is worthy of clinical promotion.
作者
刘猛
LIU Meng(Wuning Hospital of Traditional Chinese Medicine,Jiujiang 332300,China)
出处
《中国实用医药》
2024年第3期89-91,共3页
China Practical Medicine
