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正常胸腰骶脊柱三维有限元模型的建立与有效性验证

Establishment and validation of three-dimensional finite element model of normal thoracolumbosacral spine
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摘要 目的:建立包括胸椎、腰椎及骶骨在内的正常脊柱三维有限元模型,并验证其有效性,为生物力学研究和模拟手术提供可靠模型。方法:招募1名健康成年男性志愿者,对其脊柱进行CT扫描,针对其脊柱CT数据,通过Mimics、Geomagic、Solidworks、ANSYS Workbench软件重建三维有限元模型,并加载正常人体直立状态的载荷,通过计算机运算该模型在前屈、后伸、左侧屈、右侧屈、左旋转、右旋转时的活动范围(ROM),与已有的大体标本实验结果对比,来验证该模型的有效性。结果:重建了包括胸椎、腰椎及骶骨在内的正常人体脊柱,并模拟了包括皮质骨、松质骨、椎间盘、关节软骨及韧带等结构的特性,基本反映了正常人体脊柱的力学特性,通过对比,该模型的ROM在尸体实验结果的ROM之内,验证了该模型的有效性。结论:建立的正常胸腰骶脊柱模型仿真度高,可用于深入分析复杂载荷下脊柱的生物力学研究,以及模拟手术对预估术后效果提供理论指导。 Objective To establish a 3D finite element model of normal human spine including thoracic vertebra,lumbar vertebra and sacrum,and verify its validity,so as to provide a reliable model for biomechanical study and simulated surgery.Methods A healthy adult male volunteer was recruited to perform CT scan on his spine.Based on the CT data of his spine,a 3D finite element model was reconstructed using Mimics,Geomagic,Solidworks,and ANSYS Workbench software,and a normal upright human body load was loaded.The range of motion(ROM)of the model during forward bending,backward extension,left bending,right bending,left rotation and right rotation was calculated by computer and compared with the experimental results of the existing gross specimens to verify the validity of the model.Results The normal human spine including thoracic vertebra,lumbar vertebra and sacrum was reconstructed,and the structural characteristics including cortical bone,cancellous bone,intervertebral disc,articular cartilage and ligament were simulated,which basically reflected the mechanical characteristics of normal human thoracolumbar sacral spine.By comparison,the range of motion of the model was within the range of motion of the cadaveric experiment results,which verified the effectiveness of the model.The stress distribution on the upper surface of waist 1 was observed by simulating the human body standing and 6 kinds of activities.Conclusions The established model of normal thoracolumbosacral spine has a high degree of imitation,which can be used for in-depth analysis of the biomechanical study of the spine under complex loads,and provide theoretical guidance for predicting the postoperative effect of simulated surgery.
作者 李星 龙云山 韦亚军 邓俊才 LI Xing;LONG Yunshan;WEI Yajun;DENG Juncai(Department of Orthopaedics,Affiliated Hospital of Chengdu University of Traditional Chinese Medicine,Chengdu,Sichuan610000,China;Department of Spinal Surgery,The Third Affiliated Hospital of Chengdu University of Traditional Chinese Medicine,Chengdu,Sichuan 610000,China)
出处 《医药前沿》 2024年第3期6-9,共4页 Journal of Frontiers of Medicine
基金 四川省中医药管理局科研专项课题面上项目(2023MS031)。
关键词 脊柱 有限元模型 胸椎 腰椎 骶骨 Spine Finite element model Thoracic vertebra Lumbar vertebra Sacrum
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