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MOG抗体阳性和AQP4抗体阳性视神经炎治疗方法的研究进展

Research progress in the treatment of MOG antibody positive and AQP4 antibody positive optic neuritis
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摘要 视神经炎是一种主要累及青年,以视神经各种炎性病变为特征的致盲性眼科疾病。近些年随着水通道蛋白-4抗体和髓鞘少突胶质细胞糖蛋白抗体在部分患者血清中的发现,越来越多的学者认为这两种抗体介导的视神经炎区别于多发性硬化相关性视神经炎,且分别具有独特的临床特征。本文对目前这两种特异性抗体相关视神经炎的治疗方法的相关研究进行综述,以期为临床工作提供帮助。 Optic neuritis is a blinding ophthalmic disease that mainly affects young people and is characterized by various inflammatory diseases of the optic nerve.In recent years,with the discovery of aquaporin-4 immunoglobulin G and myelin oligodendrocyte glycoprotein antibody in the serum of some patients,more and more scholars believe that the two kinds of antibody mediated optic neuritis are different from multiple sclerosis associated optic neuritis and have unique clinical characteristics.This article reviews the current research on the treatment methods of these two kinds of specific antibody-associated optic neuritis,in order to provide help for clinical work.
作者 王锴琦 赵洁 WANG Kaiqi;ZHAO Jie(Department of Ophthalmology,Changchun University of Traditional Chinese Medicine,Changchun,Jilin 130000,China;Department of Ophthalmology,Jilin Provincial People's Hospital,Changchun,Jilin 130000,China)
出处 《医药前沿》 2024年第3期30-32,共3页 Journal of Frontiers of Medicine
关键词 视神经炎 髓鞘少突胶质细胞糖蛋白抗体 水通道蛋白-4抗体 Optic neuritis Myelin oligodendrocyte glycoprotein antibody Aquaporin-4 immunoglobulin G
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