摘要
目的 探讨子痫前期合并胎儿生长受限(FGR)的妊娠结局及危险因素。方法 根据是否合并FGR,将子痫前期孕妇162例分为子痫前期合并FGR(观察组,73例)和不合并FGR(对照组,89例)两组,分析两组孕妇及新生儿资料。结果 与对照组比较,观察组母亲胸腔或腹腔积液发生率升高(P<0.05)。与对照组比较,观察组新生儿严重并发症、住院时长超过30 d和新生儿死亡比例均升高(P<0.05)。多因素logistic回归分析结果显示,发病时BMI低、发病孕周小及24-h尿蛋白≥2.0 g是子痫前期合并FGR的独立危险因素(P<0.05)。结论 子痫前期合并FGR更容易导致母亲和新生儿不良结局,对有高危因素的子痫前期孕妇需加强监测。
Objective To investigate the pregnancy outcome and risk factors of preeclampsia complicated with fetal growth restriction(FGR).Methods According to whether FGR was combined, 162 pregnancy women diagnosed with preeclampsia were divided into two groups of A(with FGR,73 cases) and B(without FGR,89 cases).The data of pregnant women and newborns of the two groups were analyzed.Results Compared with group B,group A had higher incidence of pleural or abdominal fluid(P<0.05).The proportions of the neonates with serious complications, neonatal death and longer hospital stay(over 30 days) were higher in group A than those in group B(P<0.05).Multivariate logistic regression analysis showed that low BMI at onset, small gestational age and 24-h urinary protein ≥2.0 g were independent risk factors for preeclampsia complicated with FGR(P<0.05).Conclusion Preeclampsia with FGR is more likely to lead to adverse maternal and neonatal outcomes.The pregnant women exhibiting high-risk factors for preeclampsia need a enhanced monitoring.
作者
余晓红
周飞飞
陈海迎
李凤英
周庆调
YU Xiaohong;ZHOU Feifei;CHEN Haiying(Department of Obstetrics and Gynecology,People's Hospital of Wenzhou,Wenzhou 325000,CHINA)
出处
《江苏医药》
CAS
2024年第1期26-28,33,共4页
Jiangsu Medical Journal
基金
温州市基础性科研项目(Y20210347)。
关键词
子痫前期
胎儿生长受限
孕周
Preeclampsia
Fetal growth restriction
Gestational age
