摘要
脑小血管病(cerebral small vessel disease,CSVD)是引起人群认知功能障碍最重要的原因之一,随着我国人口老龄化趋势的加重及医学影像技术的发展,CSVD的发病率呈逐年上升趋势,其所引起的认知功能障碍也越来越受到关注。因脑小血管病起病隐匿、进展缓慢、早期无明显临床表现,出现症状时已进入认知功能障碍的中晚期或者已经形成痴呆,往往带给患者不能逆转的损伤及沉重的医疗负担。本文就不同影像学类型脑小血管病及其MRI总负荷对认知功能的影响进行综述,进一步了解CSVD与认知功能的关系,为CSVD所致认知功能障碍的识别和预防提供帮助。
Cerebral small vessel disease(CSVD)is one of the most major causes of cognitive dysfunction.With the acceleration of population aging in China and the development of medical imaging technology,the incidence rate of CSVD has been on the rise,and related cognitive dysfunction has become an increasingly concerning issue.Due to its insidious onset,slow progression,and lack of early warning signs,CSVD is typically found when moderate or severe cognitive im‑pairment or even dementia already occurs,often causing irreversible damage and heavy medical burden to patients.This article reviews the impact of different imaging types of CSVD and total MRI load on cognitive function to further understand the relationship between CSVD and cognitive function,aiming to provide a reference for the identification and prevention of cognitive dysfunction caused by CSVD.
作者
刘发伟(综述)
吉维忠(审校)
LIU Fawei;JI Weizhong(Graduate School of Qinghai University,Xining 810001,China)
出处
《中风与神经疾病杂志》
CAS
2024年第2期179-184,共6页
Journal of Apoplexy and Nervous Diseases
基金
科技成果转化专项项目(2023-SF-107)。
关键词
脑小血管病
MRI总负荷
认知功能障碍
Cerebral small vessel disease
Total MRI load
Cognitive impairment
