摘要
目的 观察通督泄热刺络拔罐法对湿热型强直性脊柱炎(AS)患者疼痛程度、血清炎症因子的影响。方法 将120例湿热型AS患者按照随机数字表法分为2组,对照组60例予常规西药治疗,治疗组60例在对照组治疗基础上予通督泄热刺络拔罐法治疗。2组均治疗8周。比较2组治疗前及治疗2、4、8周胸廓活动度、脊柱活动度、血清炎症因子[肿瘤坏死因子α(TNF-α)、C反应蛋白(CRP)、白细胞介素6(IL-6)]、疼痛视觉模拟评分(VAS)、强直性脊柱炎病情活动度评分(ASDAS)。结果 治疗组治疗2、4、8周后及对照组治疗4、8周后胸廓活动度、脊柱活动度均较本组治疗前增高(P<0.05),且治疗组治疗2、4、8周后均高于对照组同期(P<0.05)。治疗组治疗2、4、8周后及对照组治疗4、8周后血清TNF-α、CRP、IL-6均较本组治疗前降低(P<0.05),且治疗组治疗2、4、8周后均低于对照组同期(P<0.05)。治疗组治疗2、4、8周后及对照组治疗4、8周后疼痛VAS、ASDAS评分均较本组治疗前降低(P<0.05),且治疗组治疗2、4、8周后均低于对照组同期(P<0.05)。结论 通督泄热刺络拔罐法可有效缓解湿热型AS患者疼痛感,改善脊柱、胸廓活动度,减轻炎性反应,治疗效果显著,具有一定的临床价值。
Objective To observe the effects of Tongdu Xiere pricking-cupping on pain degree and serum inflammatory factors in patients with ankylosing spondylitis(AS)of damp-heat type.Methods A total of 120 AS patients were randomly assigned into the treatment group(n=60)and the control group(n=60).All patients were managed by conventional Western medicine,and those in the treatment group were additionally treated with Tongdu Xiere pricking-cupping therapy.Treated for 8 weeks,the aim was to compare the range of motion(ROM)of thoracic spine and spinal,serum inflammatory factors including tumor necrosis factor alpha(TNF-α),C reactive protein(CRP),interleukin 6(IL-6),the scores of visual analogue scale(VAS),ankylosing spondylitis disease activity score(ASDAS)between groups,and the therapeutic effect of the two groups was assessed.Results At 2,4,8 weeks posttreatment,the ROM of thoracic spine and spinal in the both group was significantly higher than that before treatment(P<0.05),the improvement was more pronounced in the observation group than synchronous that in the control group(P<0.05),At 2,4,8 weeks posttreatment,the levels of TNF-α,CRP,IL-6 in the both group were significantly lower than those before treatment(P<0.05),the decrease was more common in the observation group than synchronous that in the control group(P<0.05).At 2,4,8 weeks posttreatment,the scores of VAS and ASDAS in the both group were significantly decreased than those before treatment(P<0.05),the decrease was obvious in the observation group than synchronous that in the control group(P<0.05).Conclusion For AS patients with damp-heat type,Tongdu Xiere pricking-cupping can effectively relieve the pain,improve the ROMs of thoracic spine and spinal,reduce inflammatory response,the therapeutic effect is significant and has certain clinical value.
作者
刘凯
刘宇飞
温博
靳宜
LIU Kai;LIU Yufei;WEN Bo;JIN Yi(Department of Orthopedics and Traumatology,Chaoyang Traditional Chinese Medicine Hospital,Beijing 100020;Department of Orthopedics and Traumatology,Beijing Hospital of Traditional Chinese Medicine,Capital Medical University,Beijing 100010)
出处
《河北中医》
2024年第2期259-262,266,共5页
Hebei Journal of Traditional Chinese Medicine
基金
北京市属医院科研培育计划项目(编号:PZ2019018)。
关键词
刺络拔罐
强直性脊柱炎
腰背痛
炎症反应
Pricking-cupping
Ankylosing spondylitis
Low back pain
Inflammatory response
