摘要
目的 预测皮质骨组织失效应变,探究不同跑步速度对大鼠股骨皮质骨力学性能的影响。方法 设定皮质骨材料失效应变阈值,针对大鼠股骨有限元模型进行三点弯曲下的断裂模拟,将每次预测所得载荷-位移曲线与同一样本实验曲线进行比较拟合,以此反演预测组织失效应变。结果 皮质骨组织失效应变在不同跑步速度下存在显著差异,说明不同跑步速度对皮质骨结构微观力学性能产生一定影响。其中组织失效应变在以12 m/min速度跑步中最大,在以20 m/min速度跑步中最小。结论 通过观测组织失效应变变化趋势,并结合皮质骨结构的宏观断裂载荷与纳观组织弹性模量变化趋势,探讨不同跑步速度对皮质骨结构力学性能的综合影响,并找到有利于提升皮质骨力学性能的跑步速度,为通过跑步锻炼提高骨强度提供理论依据。
Objective To predict the tissue-level failure strain of the cortical bone and discuss the effects of different running speeds on the mechanical properties of rat femoral cortical bone.Methods The threshold for cortical bone tissue-level failure strain was assigned,and fracture simulation under three-point bending was performed on a rat femoral finite element model.The predicted load-displacement curves in each simulation were compared and fitted with the experimental data to back-calculate the tissue-level failure strain.Results The cortical bone tissue-level failure strains at different running speeds were statistically different,which indicated that different running speeds had certain impacts on the micromechanical properties of the cortical bone structures.At a running speed of 12 m/min,the cortical bone structure expressed the greatest tissue-level failure strain,and at a running speed of 20 m/min,the cortical bone structure expressed the lowest tissue-level failure strain.Conclusions Based on the changing trends of tissue-level failure strain and in combination with the changes in macro-level failure load and tissue-level elastic modulus of cortical bone structures,the effects of different running speeds on the mechanical properties of cortical bone structures were discussed in this study.The appropriate running speed for improving the mechanical properties of the cortical bone was explored,thereby providing a theoretical basis for improving bone strength through running exercises.
作者
范若寻
王伟军
贾政斌
FAN Ruoxun;WANG Weijun;JIA Zhengbin(Department of Traffic Engineering,Yangzhou Polytechnic Institute,Yangzhou 225127,Jiangsu,China;College of Aerospace Engineering,Jilin Institute of Chemical Technology,Jilin 132022,Jilin,China;School of Biological Science and Medical Engineering,Beihang University,Beijing 100191,China)
出处
《医用生物力学》
CAS
CSCD
北大核心
2024年第1期62-68,共7页
Journal of Medical Biomechanics
基金
吉林省自然科学基金项目(YDZJ202301ZYTS250)。
关键词
皮质骨
跑步速度
三点弯曲
断裂
组织失效应变
cortical bone
running speed
three-point bending
fracture
tissue-level failure strain
