摘要
目的:探讨乳腺癌患者经济毒性现状及其对生存质量的影响。方法:采用一般资料调查表、患者报告结局的经济毒性综合评分量表(COST-PROM)、乳腺癌患者生存质量测定量表(FACT-B)对天津市某三级甲等医院乳腺肿瘤内科住院的210例乳腺癌患者进行调查。结果:乳腺癌患者经济毒性得分为18.00(12.00,23.00)分,65.7%的患者存在经济毒性;乳腺癌患者生存质量得分为(77.99±22.65)分。Spearman相关分析显示,经济毒性总分与生存质量总分呈正相关(r=0.567,P<0.01)。多元线性回归分析显示,是否化学治疗及经济毒性是生存质量的影响因素,可解释总体变异的43.3%。结论:乳腺癌患者普遍存在经济毒性,化学治疗、经济毒性可以显著预测其生存质量。护理工作者可通过实施针对性措施,减轻化疗相关不良反应,降低经济毒性水平,从而改善其生存质量。
Objective:To explore the current status of financial toxicity in patients with breast cancer and its impact on quality of life.Methods:The general information questionnaire,the Comprehensive Score for Financial Toxicity based on the Patient-Report Outcome Measures(COST-PROM),and the Functional Assessment of Cancer Therapy-Breast(FACT-B)were used to investigate 210 patients with breast cancer hospitalized in the department of breast oncology in a Class A tertiary hospital in Tianjin.Results:Patients with breast cancer scored 18.00(12.00,23.00)points in financial toxicity and(77.99±22.65)points in quality of life.65.7%of patients had financial toxicity.Spearman correlation analysis showed that the total score of financial toxicity was positively correlated with the total score of quality of life(r=0.567,P<0.01).Multiple linear regression analysis showed that chemotherapy and financial toxicity were the influencing factors of quality of life and explained 43.3%of the overall variation.Conclusion:The financial toxicity in patients with breast cancer is common.Chemotherapy and financial toxicity can significantly predict patients′quality of life.Nurses can implement targeted measures to reduce chemotherapy-related adverse reactions and reduce the level of financial toxicity,thereby improving patients′quality of life.
作者
焦娜娜
任海玲
JIAO Nana;REN Haiing(Tianjin Medical University Cancer Institute and Hospital,Tianjin,300060)
出处
《天津护理》
2024年第1期43-48,共6页
Tianjin Journal of Nursing
关键词
乳腺癌
经济毒性
生存质量
Breast cancer
Financial toxicity
Quality of life
