摘要
目的 探讨膜状胎盘发病机制及对妊娠结局的影响。方法 检索2010年4月至2021年6月甘肃省妇幼保健院产前检查并住院终止妊娠的170 621例孕妇的临床资料,选取其中产前超声诊断并经产后病理证实的19例膜状胎盘或部分性膜状胎盘病人作为研究对象。查阅病历收集19例孕妇的年龄、孕次、孕周、超声检查资料、胎儿宫内生长情况、终止妊娠的孕周、分娩方式、产前及产后出血情况及围产儿结局等资料进行回顾性分析。结果 膜状胎盘的发生率0.011 1%(19/170 621),其中既往有刮宫史12例、胎儿生长受限的16例、羊水过少15例、15例出现脐动脉血流异常、11例出现产前出血、引产经阴道分娩16例、剖宫产3例;围产儿17例死胎分娩、2例新生儿存活。结论 膜状胎盘可导致早产、流产、胎死宫内、羊水过少、胎儿宫内生长受限等严重不良围产儿结局,也可导致产前及产后大量出血,对于膜状胎盘孕妇,需要制定合理的诊疗方案,早诊断,早干预。
Objective To explore the pathogenesis of membranous placenta and its influence on pregnancy outcome.Methods The clinical data of 170 621 pregnant women who underwent prenatal examination and were hospitalized to terminate pregnancy in Gansu Provincial Maternity and Child Care Hospital from April 2010 to June 2021 were retrieved.19 patients with placenta membranacea or partial placenta membranacea diagnosed by prenatal ultrasound and confirmed by postpartum pathology were selected as the research objects.The age,gestational times,gestational weeks,ultrasound data,intrauterine growth,gestational weeks of termination of pregnancy,mode of delivery,prenatal and postpartum hemorrhage and perinatal outcomes of 19 pregnant women were collected and analyzed retrospectively.Results The incidence of placenta membranacea was 0.011 1%(19/170 621).Among them,there were 12 cases of curettage,16 cases of fetal growth restriction,15 cases of oligohydramnios,15 cases of abnormal umbilical artery blood flow,11 cases of prenatal bleeding,16 cases of induced labor,transvaginal delivery and 3 cases of cesarean section,17 perinatal infants were stillborn and 2 newborns survived.Conclusions Placenta membranacea can lead to serious adverse perinatal outcomes such as preterm birth,abortion,intrauterine fetal death,oligohydramnios and intrauterine growth restriction,and can also lead to massive prenatal and postpartum hemorrhage.For pregnant women with placenta membranacea,it is necessary to formulate reasonable diagnosis and treatment plans,early diagnosis and early intervention.
作者
刘小晖
李莲英
王玥元
董燕
高丽娜
刘小玲
何晓春
孟照琰
LIU Xiaohui;LI Lianying;WANG Yueyuan;DONG Yan;GAO Lina;LIU Xiaoling;HE Xiaochun;MENG Zhaoyan(Department of Obstetrics,Gansu Provincial Maternity and Child Care Hospital(Gansu Provincial Central Hospital),Lanzhou,Gansu 730050,China;Pathology Department,Gansu Provincial Maternity and Child Care Hospital(Gansu Provincial Central Hospital),Lanzhou,Gansu 730050,China)
出处
《安徽医药》
CAS
2024年第3期509-512,I0005,共5页
Anhui Medical and Pharmaceutical Journal
基金
甘肃省自然科学基金项目(20JR5RA135)
陇原青年创新创业人才个人项目(甘组通字[2022]77号)
兰州市科技计划项目(2023-4-64)。
关键词
胎盘疾病
膜状胎盘
超声诊断
绒毛
发病机制
妊娠结局
Placenta diseases
Placenta membranacea
Ultrasound diagnosis
Villi
Pathogenesis
Pregnancy outcome
