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氨溴索联合注射用阿莫西林克拉维酸钾治疗小儿支气管肺炎的临床效果

Clinical effect of Ambroxol combined with Amoxicillin Clavulanate Potassium for injection in the treatment of children with bronchial pneumonia
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摘要 目的探究氨溴索联合注射用阿莫西林克拉维酸钾治疗小儿支气管肺炎的临床效果。方法选取2021年5月至2023年5月蒲城县医院收治的120例支气管肺炎患儿作为研究对象,按照随机数字表法分为对照组(60例)与观察组(60例)。对照组采用氨溴索治疗,观察组在对照组基础上联合注射用阿莫西林克拉维酸钾治疗。比较两组临床疗效、炎症因子水平、临床症状消退时间及不良反应发生情况。结果治疗后,观察组临床总有效率高于对照组(P<0.05);观察组白介素-6、肿瘤坏死因子-α、超敏C反应蛋白水平低于对照组(P<0.05);观察组发热、肺部啰音、扁桃体充血、咳嗽消退时间短于对照组(P<0.05);观察组不良反应总发生率低于对照组(P<0.05)。结论氨溴索联合注射用阿莫西林克拉维酸钾治疗小儿支气管肺炎可提高临床疗效,值得推广使用。 Objective To explore the clinical effect of Ambroxol combined with Amoxicillin Clavulanate Potassium for injection in the treatment of children with bronchial pneumonia.Methods A total of 120 children with bronchial pneumonia in Pucheng County Hospital from May 2021 to May 2023 were selected as the study objects.All the children were divided into the control group(60 cases)and the observation group(60 cases)using the random number table method.The control group was treated with Ambroxol,and the observation group was treated with combined Amoxicillin Clavulanate Potassium for injection on the basis of the control group.The clinical efficacy,the levels of inflammatory factors,the resolution time of clinical symptom and the incidence of adverse reactions of the two groups were compared.Results After treatment,the total clinical effective rate in the observation group was higher than that in the control group(P<0.05).The levels of interleukin-6,tumor necrosis factor-α and hypersensitive C-reactive protein in the observation group were lower than those in the control group(P<0.05).The resolution time of fever,lung rales,tonsil congestion and cough in the observation group was shorter than that in the control group(P<0.05).The total incidence rate of adverse reactions in the observation group was lower than that in the control group(P<0.05).Conclusion Ambroxol combined with Amoxicillin and Clavulanate Potassium for injection can improve the clinical effect of children with bronchial pneumonia,and it is worth popularizing.
作者 李丽丽 韩盼盼 LI Lili;HAN Panpan(Department of Pediatrics,Pucheng County Hospital,Shaanxi Province,Pucheng 715500,China)
出处 《妇儿健康导刊》 2024年第2期105-107,111,共4页 JOURNAL OF WOMEN AND CHILDREN'S HEALTH GUIDE
关键词 氨溴索 阿莫西林克拉维酸钾 小儿支气管肺炎 Ambroxol Amoxicillin Clavulanate Potassium Children with bron chial pneumonia
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