摘要
目的探究血压昼夜节律与妊娠期高血压患者胎盘早剥的相关性,为临床提供参考。方法选取2018年1月至2022年12月广州市妇女儿童医疗中心收治的315例妊娠期高血压患者为研究对象进行回顾性分析,根据是否发生胎盘早剥将患者分为胎盘早剥组(71例)和无胎盘早剥组(244例)。收集两组患者的临床资料及24 h动态血压监测数据,比较两组患者血压昼夜节律类型,并分析24 h动态血压与胎盘早剥发生的相关性。结果胎盘早剥组患者剖宫产率高于无胎盘早剥组(P<0.05)。胎盘早剥组患者24 h平均动脉压(MAP)、夜间MAP、24 h舒张压平均值(mDBP)、白天mDBP、夜间mDBP、血压晨峰及最低血压均高于无胎盘早剥组(均P<0.05)。无胎盘早剥组患者血压昼夜节律分型主要为杓型和非杓型,胎盘早剥组患者主要为非杓型和反杓型,两组患者血压昼夜节律类型构成分布比较,差异有统计学意义(P<0.05)。Spearman相关性分析结果显示,24 h MAP、夜间MAP、24 h mDBP、白天mDBP、夜间mDBP、血压晨峰及最低血压与胎盘早剥发生均呈正相关(均P<0.05)。结论血压昼夜节律的改变与妊娠期高血压患者胎盘早剥的发生存在相关性,临床需给予重视。
Objective To explore the correlation between circadian rhythm of blood pressure and placental abruption in patients with pregnancy-induced hypertension,and to provide a clinical reference.Methods A total of 315 patients with pregnancy-induced hypertension admitted to Guangzhou Women and Children’s Medical Center from January 2018 to December 2022 were selected for retrospective analysis.According to whether placental abruption occurred,the patients were divided into the placental abruption group(71 cases)and the non-placental abruption group(244 cases).Clinical data and 24 h ambulatory blood pressure monitoring data of the two groups were collected,the blood pressure circadian rhythm types of the two groups were compared,and the correlation between 24 h ambulatory blood pressure and placental abruption was analyzed.Results The rate of cesarean section in the placental abruption group was higher than in the non-placental abruption group(P<0.05).The 24 h mean arterial pressure(MAP),night MAP,24 h mean diastolic blood pressure(mDBP),daytime mDBP,night mDBP,morning peak,and minimum blood pressure of patients in the placental abruption group was higher than those in the non-placental abruption group(P<0.05).The blood pressure circadian rhythm of the non-placental abruption group were mainly divided into arytenoid and non-arytenoid,and the placental abruption group were mainly divided into non-arytenoid and reverse arytenoid.There were statistically significant differences in the composition and distribution of blood pressure circadian rhythm between the two groups(P<0.05).Spearman correlation analysis showed that 24 h MAP,night MAP,24 h mDBP,day mDBP,night mDBP,morning peak,and minimum blood pressure were positively correlated with placental abruption(P<0.05).Conclusion The change of the circadian rhythm of blood pressure is correlated with placental abruption in patients with pregnancy-induced hypertension,which needs clinical attention.
作者
丁文
殷为
张国正
DING Wen;YIN Wei;ZHANG Guozheng(Department of Obstetrics,Guangzhou Women and Children's Medical Center,Guangzhou,510630,Guangdong,China)
出处
《大医生》
2024年第3期27-30,共4页
Doctor
关键词
血压昼夜节律
妊娠期高血压
胎盘早剥
Circadian rhythm of blood pressure
Pregnancy-induced hypertension
Placental abruption
