摘要
目的探究重度子痫前期(severe preeclampsia,sPE)出现心功能不全相关的危险因素。方法选取2020年1月至2023年9月于温州市中心医院住院的sPE并发心功能不全的患者32例作为实验组,并随机选取同时期心功能正常的sPE患者75例作为对照组。比较两组患者的一般资料和实验室指标的差异,采用二元Logistic回归分析探讨sPE出现心功能不全的危险因素。结果实验组患者出现呼吸衰竭、血管内溶血-肝酶升高-低血小板、感染的例数高于对照组,差异有统计学意义(P<0.05)。对照组发生新生儿窒息、新生儿转重症监护的例数高于实验组,差异有统计学意义(P<0.05)。两组患者的孕前体质量指数、孕期体质量增幅、血钙、白蛋白、血红蛋白、双胎、感染差异有统计学意义(P<0.05),二元Logistic回顾分析结果显示,孕前体质量指数增加、孕期体质量增幅≥20kg、低血钙、低白蛋白、中度贫血、孕期血压增加是sPE出现心功能不全的危险因素。结论孕期应积极控制血压、补钙、补铁、补充白蛋白、控制体质量;对sPE患者增加血钙、白蛋白、血红蛋白、血压相关指标监测的频率,积极控制血压、解痉、预防感染可减少sPE患者心功能不全的发生。
Objective To explore the risk factors related to cardiac insufficiency in severe preeclampsia(sPE).Methods A total of 32 patients with sPE complicated with heart failure who were hospitalized at Wenzhou Central Hospital from January 2020 to September 2023 were selected as experimental group,and 75 sPE patients with normal heart function during the same period were randomly selected as control group.Compare the differences in general information and laboratory indicators between two groups of patients,and use binary logistic regression analysis to explore the risk factors for cardiac dysfunction in sPE.Results The experimental group of patients exhibited respiratory failure,hemolysis,elevated liverenzymes,and low platelets,as well as a higher incidence of infections compared to the control group,with statistically significant differences(P<0.05).The control group had a higher incidence of neonatal asphyxia and neonatal transfer to intensive care compared to the experimental group,with statistically significant differences(P<0.05).There were statistically significant differences(P<0.05)between the two groups in terms of pre-pregnancy body-mass index,weight gain during pregnancy,blood calcium,albumin,hemoglobin,twin pregnancy,and infection.Binary logistic regression analysis revealed that increased pre-pregnancy body-mass index,weight gain during pregnancy≥20kg,low blood calcium,low albumin,moderate anemia,and increased blood pressure during pregnancy were risk factors for the occurrence of heart failure in patients with sPE.Conclusion During pregnancy,it is important to actively control blood pressure,supplement calcium and iron,and maintain proper weight.For sPE patients,increasing the frequency of monitoring blood calcium,albumin,hemoglobin,and blood pressure-related indicators,actively controlling blood pressure,administering spasmolytic agents,and preventing infections can reduce the occurrence of heart failure.
作者
吴秀秀
胡文胜
沈旭娜
占思思
WU Xiuxiu;HU Wensheng;SHEN Xu’na;ZHAN Sisi(Graduate School of Obstetrics and Gynecology,Zhejiang Chinese Medical University,Hangzhou 310056,Zhejiang,China;Department of Obstetrics and Gynecology,Wenzhou Central Hospital,Wenzhou 325100,Zhejiang,China;Department of Obstetrics and Gynecology,Zhejiang University School of Medicine Affiliated Obstetrics and Gynecology Hospital,Hangzhou 310003,Zhejiang,China)
出处
《中国现代医生》
2024年第6期63-66,共4页
China Modern Doctor
