摘要
目的分析不同急诊救治措施在糖尿病酮症酸中毒患者临床干预中的可行性。方法选择2020年4月—2023年4月漳浦天福医院收治的50例糖尿病酮症酸中毒患者为研究对象,采用随机数表法分为对照组和观察组,每组25例。两组患者均采取相同的补液、补钾以及纠正酮症酸中毒的干预,在此基础上,对照组患者采取胰岛素静脉滴注治疗,观察组患者采用胰岛素泵治疗,比较两组患者的急诊救治效果。结果观察组尿酮转阴、pH值恢复正常、酸中毒纠正的时间分别为(1.15±0.24)d、(3.27±0.43)h、(5.31±0.46)d,均优于对照组,差异有统计学意义(t=7.939、10.112、6.013,P均<0.001)。治疗后,观察组炎症因子水平低于对照组,差异有统计学意义(P均<0.05)。观察组病死率为0,并发症发生率为12.0%,均低于对照组,差异有统计学意义(χ^(2)=5.556、6.825,P均<0.05)。结论在糖尿病酮症酸中毒患者急诊救治期间,在常规临床干预的基础上实施胰岛素泵治疗方法可显著改善患者临床症状,并且与单纯注射胰岛素相比,该疗法的安全性更高,更有助于挽救患者生命。
Objective To analyze the feasibility of different emergency treatment measures in clinical intervention of diabetic ketoacidosis patients.Methods Fifty patients with diabetic ketoacidosis admitted to Zhangpu Tianfu Hospital from April 2020 to April 2023 were selected as the study objects,and were divided into control group and observation group by random number table method,with 25 cases in each group.Two groups of patients were treated with the same fluid supplement,potassium supplement and intervention to correct ketoacidosis.On this basis,patients in the control group were treated with insulin intravenous infusion,and patients in the observation group were treated with in-sulin pump.The emergency treatment effect of the two groups was compared.Results The time for urine ketone to turn negative,pH value to return to normal and acidosis correction in the observation group were(1.15±0.24)d,(3.27±0.43)h and(5.31±0.46)d,respectively,which were better than those in the control group,and the differences were sta-tistically significant(t=7.939,10.112,6.013,all P<0.001).After treatment,the level of inflammatory factors in the ob-servation group were lower than those in the control group,and the difference was statistically significant(all P<0.05).The mortality rate and complication rate of observation group were 0 and 12.0%respectively,which were lower than those of control group,and the differences were statistically significant(χ^(2)=5.556,6.825,both P<0.05).Conclusion During the emergency treatment of patients with diabetic ketoacidosis,the implementation of insulin pump therapy based on routine clinical intervention can significantly improve the clinical symptoms of patients,and compared with insulin injection alone,this therapy is safer and more helpful to save patients'lives.
作者
林炎兴
王萃毅
谭国清
LIN Yanxing;WANG Cuiyi;TAN Guoqing(Zhangpu Tianfu Hospital,Zhangzhou,Fujian Province,363000 China;Zhangpu County Hospital,Zhangzhou,Fujian Province,363000 China)
出处
《糖尿病新世界》
2023年第24期163-166,共4页
Diabetes New World Magazine
关键词
糖尿病酮症酸中毒
急诊救治
胰岛素泵
临床症状
Diabetic ketoacidosis
Emergency treatment
Insulin pump
Clinical signs and symptoms
