摘要
目的 探讨结直肠癌患者术前营养风险指数(NRI)对其术后腹腔感染的预测价值。方法 前瞻性纳入2019年4月至2022年4月漯河医学高等专科学校第三附属医院收治的125例接受腹腔镜根治术治疗的结直肠癌患者为研究对象,进行相关检查,计算患者术前NRI。术后进行14 d随访,根据患者随访期间术后腹腔感染发生情况分为发生组和未发生组。经logistic回归分析检验结直肠癌患者术前NRI与术后腹腔感染的关系,并探究其对患者术后腹腔感染的预测价值。结果 125例患者中31例(24.80%)出现术后并发腹腔感染,94例(75.20%)未发生术后腹腔感染。两组患者术前NRI、手术时间、肿瘤TNM分期比较,差异有统计学意义(P<0.05);组间其他一般资料比较,差异无统计学意义(P>0.05)。logistic回归分析结果显示,肿瘤TNM分期Ⅲ期是结直肠癌患者术后腹腔感染的危险因素(OR>1,P<0.05),术前NRI高是结直肠癌患者发生术后腹腔感染的保护因素(OR<1,P<0.05)。绘制受试者工作特征曲线,结果显示,术前NRI预测结直肠癌患者发生术后腹腔感染的AUC≥0.7,具有一定预测价值,且当其取最佳阈值90.770时,可获得最佳预测价值。结论 术前NRI低会增加结直肠癌患者术后腹腔感染发生风险,检测术前NRI预测患者术后腹腔感染发生风险。
Objective To explore the predictive value of preoperative nutritional risk index(NRI)for postoperative abdominal infections in colorectal cancer patients.Methods A prospective study was conducted on 125 colorectal cancer patients who underwent laparoscopic radical surgery and were admitted to the Third Affiliated Hospital of Luohe Medical College from April 2019 to April 2022.Relevant examinations were conducted and preoperative NRI was calculated.After 14 days of follow-up,patients were divided into two groups based on the incidence of postoperative abdominal infections during the follow-up period:the occurrence group and the non-occurrence group.Logistic regression analysis was used to examine the relationship between preoperative NRI and postoperative abdominal infection in patients with colorectal cancer,and to explore its predictive value for postoperative abdominal infection.Results Among the 125 patients,31(24.80%)experienced postoperative abdominal infection,while 94(75.20%)did not experience postoperative abdominal infection.There was statistically difference in preoperative NRI,surgical time and tumor TNM staging between the two groups of patients(P<0.05),and there was no statistically difference in other general data between groups(P>0.05).The results of logistic regression analysis showed that tumor TNM stage III was a risk factor for postoperative abdominal infection in colorectal cancer patients(OR>1,P<0.05),and high preoperative NRI was the protective factor for postoperative abdominal infection in colorectal cancer patients(OR<1,P<0.05).The receiver operating characteristic curve was drawed,and the results showed that AUC of NRI≥0.7,which has certain predictive value for postoperative abdominal infection in colorectal cancer patients.When the optimal threshold value of 90.770 was taken,the best predictive value could be obtained.Conclusion Low preoperative NRI can increase the risk of postoperative abdominal infection in patients with colorectal cancer.Early detection of preoperative NRI can be used to predict the risk of postoperative abdominal infection in patients.
作者
朱利伟
关小静
潘书辉
李旭静
ZHU Liwei;GUAN Xiaojing;PAN Shuhui;LI Xujing(Minimally Invasive Surgery Department,the Third Affiliated Hospital of Luohe Medical College,Luohe 462000,China)
出处
《河南医学研究》
CAS
2024年第3期466-469,共4页
Henan Medical Research
关键词
结直肠癌
营养风险指数
腹腔感染
预后
预测价值
colorectal cancer
nutrition risk index
abdominal infection
prognosis
predictive value
