摘要
目的 分析急性冠脉综合征(ACS)合并恶性肿瘤患者经冠脉介入术后的预后。方法 回顾性分析84例行冠脉介入术治疗的ACS合并恶性肿瘤患者的病历有关资料。在患者行冠脉介入术治疗后进行2年随访,依据患者的临床结局将其分为生存组与死亡组。运用多因素Logistic回归分析模型探究ACS合并恶性肿瘤患者行冠脉介入术治疗后死亡的影响因素。结果 随访2年,84例行冠脉介入术治疗的ACS合并恶性肿瘤患者中,共14例死亡,70例生存。单因素分析显示:年龄、性别、高血压、体重指数(BMI)、陈旧性心肌梗死、高脂血症、血红蛋白(HB)、肠外抗凝治疗与ACS合并恶性肿瘤患者冠脉介入术后死亡无关(P>0.05),糖尿病、吸烟、脑钠肽(BNP)水平、血小板计数(PLT)与ACS合并恶性肿瘤患者冠脉介入术后死亡有关(P<0.05);多因素Logistic回归分析显示:糖尿病(OR=9.167,95%CI=2.311~36.360)、吸烟(OR=16.105,95%CI=3.294~78.734)、BNP水平升高(OR=19.759,95%CI=4.634~359.79)、PLT减少(OR=18.231,95%CI=3.954~230.64)为ACS合并恶性肿瘤患者冠脉介入术后死亡的主要影响因素(P<0.05)。结论 ACS合并恶性肿瘤患者经冠脉介入治疗后死亡率较高,死亡的发生与糖尿病、吸烟、BNP水平升高、PLT减少有关,临床需予以高度重视,并针对性开展医疗干预,以最大程度改善患者预后。
Objective To analyze the prognosis of patients with acute coronary syndrome(ACS)complicated with malignant tumors after coronary intervention surgery.Methods A retrospective analysis was conducted on the medical records of 84 patients with ACS complicated with malignant tumors who underwent coronary intervention therapy.After underwent coronary intervention treatment,patients were followed up for 2 years and divided into survival and death groups based on their clinical outcomes.Using a multivariate logistic regression analysis model to explore the influencing factors of mortality in patients with ACS complicated with malignant tumors underwent coronary intervention therapy.Results Followed up for 2 years,out of 84 ACS patients with malignant tumors treated with coronary intervention,a total of 14 died and 70 survived;Univariate analysis showed that age,sex,hypertension,body mass index(BMI),old myocardial infarction,hyperlipidemia,hemoglobin(HB),and parenteral anticoagulant therapy were not related to the death of ACS patients with malignant tumor after coronary intervention(P>0.05),while diabetes,smoking,brain natriuretic peptide(BNP)level,and platelet count(PLT)were related to the death of ACS patients with malignant tumor after coronary intervention(P<0.05);Multivariate logistic regression analysis showed that diabetes(OR=9.167,95%CI=2.311~36.360),smoking(OR=16.105,95%CI=3.294~78.734),increased BNP level(OR=19.759,95%CI=4.634~359.79),and decreased PLT(OR=18.231,95%CI=3.954~230.64)were the main factors influencing the death of ACS patients with malignant tumors after coronary intervention(P<0.05).Conclusion The mortality rate of ACS patients with malignant tumor after coronary intervention treatment is high.The occurrence of death is related to diabetes,smoking,the increase of BNP level,and the decrease of PLT.Clinical attention should be paid and targeted medical intervention should be carried out to improve the prognosis of patients to the greatest extent.
作者
张娟
徐雪飞
张莎莎
韩大臻
ZHANG Juan;XU Xuefei;ZHANG Shasha(Henan Provincial Chest Hospital,Zhengzhou,450003)
出处
《实用癌症杂志》
2024年第3期502-504,508,共4页
The Practical Journal of Cancer
关键词
急性冠脉综合征
恶性肿瘤
冠脉介入术
预后
Acute coronary syndrome
Malignant tumors
Coronary intervention surgery
Prognosis
