摘要
目的 观察超敏C反应蛋白(hs-CRP)、白细胞计数(WBC)、中性粒细胞百分比与社区获得性肺炎(CAP)的相关性。方法选取2021年1月至2022年12月收治的社区获得性肺炎患者共计90例为研究对象,回顾性分析,根据肺炎严重程度指数(PSI)不同,将患者分为三组,轻度组(30例)、中度组(30例)、重度组(30例),所有患者均进行hs-CRP、WBC、中性粒细胞百分比检测,观察检验结果差异,对hs-CRP、WBC、中性粒细胞百分比同社区获得性肺炎的相关性进行分析。并持续跟踪90例患者治疗情况,分析hs-CRP、WBC、中性粒细胞百分比同初始治疗效果的相关性。结果 治疗前,三组hs-CRP、WBC、中性粒细胞百分比对比差异有统计学意义(P <0.05);重度组hs-CRP、WBC高于中度组、轻度组(P <0.05);中度组hs-CRP、WBC、中性粒细胞百分比高于轻度组(P <0.05)。Spearman相关分析结果显示,WBC、hs-CRP同PSI程度正相关(P <0.05),中性粒细胞百分比同PSI程度相关性不强(P> 0.05)。轻度组初始治疗有效率高于中度组、重度组(P <0.05)。多因素Logistic回归分析显示治疗3 d的hs-CRP、治疗3 d的WBC为初始治疗失败的危险因素(P <0.05)。结论 CAP严重程度同hs-CRP、WBC、中性粒细胞百分比具有一定相关性,可通过观察患者hs-CRP水平指导初始治疗。
Objective To investigate the correlation between hypersensitive C-reactive protein,white blood cell count,neutrophil percentage and community-acquired pneumonia(CAP).Methods A total of 90 patients with community-acquired pneumonia admitted to our hospital from January 2021 to December 2022 were the study objects.According to the different pneumonia severity index(PSI),the patients were divided into three groups:mild group(30 cases),moderate group(30 cases) and severe group(30 cases).Hypersensitive C-reactive protein(hs-CRP),white blood cell count(WBC),and neutrophil percentage were detected in all patients.The differences in test results were observed,and the correlation between hs-CRP,WBC,and neutrophil percentage and community-acquired pneumonia was analyzed.The treatment status of 90 patients was continuously followed up,and the correlation between hs-CRP,WBC,neutrophil percentage and initial treatment effect was analyzed.Results Before treatment,the differences in the comparison of hs-CRP,WBC,and neutrophil percentage among the three groups were statistically significant(P<0.05);hs-CRP and WBC in the severe group were higher than those in the moderate group and the mild group(P<0.05);and hs-CRP,WBC,and neutrophil percentage in the moderate group were higher than those in the mild group(P<0.05).The results of Spearman's correlation analysis showed that WBC and hs-CRP were positively correlated with the degree of PSI(P<0.05),and the percentage of neutrophils was not strongly correlated with the degree of PSI(P<0.05).The effective rate of initial treatment in the mild group was higher than that in the moderate and severe groups(P<0.05).Multifactorial logistic regression analysis showed that hs-CRP at 3 d of treatment and WBC at 3 d of treatment were risk factors for initial treatment failure(P<0.05).Conclusions The severity of CAP is correlated with hs-CRP,WBC and neutrophil percentage.The initial treatment can be guided by observing the hs-CRP level of patients.
作者
陈金星
CHEN Jinxing(Department of Clinical Laboratory,Yongtai County Hospital,Fuzhou 350700,China)
出处
《中国医药指南》
2024年第7期112-114,共3页
Guide of China Medicine
关键词
社区获得性肺炎
超敏C反应蛋白
白细胞计数
中性粒细胞百分比
Community-acquired pneumonia
High sensitivity C-reactive protein
White blood cell count
Neutrophil percentage
