摘要
目的分析不同浓度、注射速率的非离子型碘对比剂成像效果及不良反应,为临床CT检查中正确选择用药、扫描方案及不良反应处理提供依据。方法随机选择12500例使用非离子型碘对比剂患者,根据常用的三种对比剂使用模式,将患者分为A(2780例)、B(6230例)、C(3490例)组。A组采用碘帕醇370 mg/L,速率5 mL/s;B组采用碘海醇300 mg/L,速率3 mL/s;C组采用碘克沙醇270 mg/L,速率2.5 mL/s。比较三组的影像图像质量、对比剂渗漏及不良反应发生情况。结果三组患者的图像质量不合格153例,占比1.22%(153/12500);图像质量合格12347例,占比98.78%(12347/12500)。三组患者的图像质量合格率比较,差异无统计学意义(P>0.05)。三组患者对比剂渗漏25例,发生率为0.20%(25/12500);A组对比剂渗漏17例,发生率为0.61%(17/2780);B组对比剂渗漏7例,发生率为0.11%(7/6230);C组对比剂渗漏1例,发生率为0.03%(1/3490);三组患者的对比剂渗漏发生率比较,差异具有统计学意义(P<0.005)。三组患者共发生不良反应97例,占比0.78%(97/12500),其中轻度反应84例,占比0.67%(84/12500);中度反应13例,占比0.10%(13/12500);无重度不良反应。三组患者的不良反应总发生率比较,差异具有统计学意义(P<0.005);B组的不良反应总发生率低于A组,差异具有统计学意义(P<0.05)。结论预防和处理非离子型碘对比剂的应用风险是目前CT扫描中一个十分重要的问题;从非离子型碘对比剂不良反应风险预防、对比剂渗漏风险预防与护理等方面加以分析,可在确保获得最佳图像效果的同时保证患者安全。
Objective To analyze the imaging effects and adverse reactions of non-ionic iodine contrast agent with different concentrations and injection rates in CT examination,and provide basis for the correct selection of drugs,scanning schemes and adverse reactions in clinical CT examination.Methods A total of 12500 patients with non-ionic iodine contrast agent were randomly selected.According to the three commonly used contrast agent use patterns,the patients were divided into group A(2780 cases),group B(6230 cases)and group C(3490 cases).The group A was treated with iopamidol 370 mg/L at a rate of 5 mL/s;the group B was treated with iohexol 300 mg/L at a rate of 3 mL/s;the group C was treated with iodixanol 270 mg/L at a rate of 2.5 mL/s.The image quality,contrast agent leakage and adverse reactions of the three groups were compared.Results The image quality of the three groups of patients was unqualified in 153 cases,accounting for 1.22%(153/12500);the image quality was qualified in 12347 cases,accounting for 98.78%(12347/12500).There was no significant difference in the qualified rate of image quality among the three groups(P>0.05).There were 25 cases of contrast agent leakage in the three groups,with an incidence of 0.20%(25/12500).There were 17 cases of contrast agent leakage in the group A,with an incidence of 0.61%(17/2780);there were 7 cases of contrast agent leakage in the group B,and the incidence rate was 0.11%(7/6230);there was 1 case of contrast agent leakage in the group C,and the incidence rate was 0.03%(1/3490);there was a statistically significant difference in the incidence of contrast agent leakage among the three groups(P<0.005).There were 97 cases of adverse reactions in the three groups,accounting for 0.78%(97/12500),including 84 cases of mild reactions,accounting for 0.67%(84/12500);13 cases of moderate reactions,accounting for 0.10%(13/12500);and no severe adverse reactions.The total incidence of adverse reactions in the three groups was statistically significant(P<0.005);the total incidence of adverse reactions in the group B was lower than that in the group A,and the difference was statistically significant(P<0.05).Conclusion Prevention and treatment of the application risk of non-ionic iodine contrast agent is a very important issue in CT scan.Analysis from the aspects of risk prevention of adverse reactions of non-ionic iodine contrast agent,risk prevention and nursing of contrast agent leakage can ensure the safety of patients while ensuring the best image effect.
作者
胡承涛
淳彩雯
HU Chengtao;CHUN Caiwen(Xinhua Hospital of Yili Prefecture,Yining 835000,China)
出处
《临床医学研究与实践》
2024年第7期61-64,共4页
Clinical Research and Practice
基金
伊犁哈萨克自治州科技计划项目(No.YZ2020YD010)。
关键词
非离子型碘对比剂
CT成像技术
对比剂渗漏
non-ionic iodine contrast agent
CT imaging technology
contrast agent leakage
