摘要
目的:研究佛山地区成年人椎体骨密度(BMD)与性别、年龄的关系,探讨本地区不同年龄段BMD均值及各年龄段骨质疏松症(OP)的发病率。方法:对佛山市中医院2021年10月至2023年3月的1 065例(男性648例,女性417例)健康成年人体检者使用定量CT(QCT)行椎体BMD检测,按年龄段进行分组;采用t检验和方差分析对不同性别、不同年龄段BMD值进行检验,采用χ2检验和相关分析对不同性别、不同年龄段的OP发病率进行分析。结果:20~29岁、30~39岁、40~49岁及60~69岁、70~79岁不同性别间的BMD差异均有统计学意义,女性BMD在青中年时期高于男性。在40~49岁、50~59岁、60~69岁、70~79岁男性组及30~39、40~49岁、50~59岁、60~69岁女性组中,同性别不同年龄段间的BMD值差异有统计学意义,且随年龄的增长呈下降趋势;同性别不同年龄段的OP发病率差异均有统计学意义,年龄与OP发病率呈正相关关系(r男=0.517,r女=0.636)。结论:佛山市健康成年人QCT测量的椎体BMD与性别、年龄相关,在20~29岁达到峰值,随年龄的增长而下降;从40~49岁开始,OP发病率在男性和女性中随着年龄的增长而增加。
Objective:To study the relation between adult vertebral bone mineral density(BMD)and gender and age in Foshan,to explore the average BMD of each age group and osteoporosis(OP)incidence distribution in the region.Methods:Quantitative computed tomography(QCT)was used to examine and record the vertebral BMD of 1065(male 648,female 417)healthy adults who underwent physical examination in Foshan Hospital of TCM from October 2021 to March 2023,and grouped according to age,T test and variance analysis were used on BMD in different sex and age group.Chi square analysis and correlation analysis were used on the incidence of OP in different sex and age group.Results:There was significant difference in the BMD between male and female of 20~29,30~39,40~49 and 60~69,70~79 years old,women had higher peak BMD than man in young to middle age.In the male groups of 40~49、50~59,60~69,70~79 and female groups of 30~39,40~49,50~59,60~69 years old,there were also significant differences in BMD in different age groups of the same sex,and decreased with age.There was significant difference in the incidence of OP between different age groups in the male and female groups.Age was positively related to the incidence of OP(r=0.517 for male and r=0.636 for female).Conclusion:The vertebral BMD derived from QCT for healthy adults in Foshan are associated with sex and age,peaked at 20~29 years old,and decreased with age.The incidence of OP for male and female increased with age from 40~49 years old.
作者
吴伟智
方挺松
梁振华
祝翠玲
周静仪
WU Weizhi;FANG Tingsong;LIANG Zhenhua;ZHU Cuiling;ZHOU Jingyi(Department of Radiology,Foshan Hospital of TCM,Foshan 528000,China)
出处
《CT理论与应用研究（中英文）》
2024年第2期213-220,共8页
Computerized Tomography Theory and Applications
基金
2022年佛山市自筹经费类科技创新项目入库培育项目(2220001004568)
佛山市“十四五”医学重点专科项目(FSZD145011)。
关键词
定量CT
骨密度
骨质疏松症
相关性
quantitative CT(QCT)
bone mineral density(BMD)
osteoporosis(OP)
correlation
