摘要
慢性萎缩性胃炎(Chronic atrophic gastritis,CAG)是以胃黏膜固有腺体减少、萎缩为基本特征的一种慢性胃部疾病。长期慢性的非可控炎症使得胃黏膜长时间处于高炎性反应状态,或可诱导胃恶性肿瘤的发生,该过程为胃“炎癌转化”。目前中医药治疗CAG临床疗效确切,能有效延缓甚至逆转胃“炎癌转化”,本文从中医药改善胃黏膜萎缩和改善肿瘤形成前微环境两方面来探讨其治疗CAG的机制,以期为中医药治疗CAG、干预“炎癌转化”、逆转癌前病变提供证据支持及治疗思路。
Chronic atrophic gastritis(CAG)is a chronic gastric disease characterized by the reduction and atrophy of the inherent glands of the gastric mucosa.However,long-term non-controllable inflammation makes the gastric mucosa in a state of high inflammatory response for a long time,which can induce the occurrence of gastric malignant tumors.This process is called the"inflammatory cancer transformation"of the stomach.At present,the clinical efficacy of traditional Chinese medicine in the treatment of CAG is certain,which can effectively delay or even reverse the"inflammatory cancer transformation".But the mechanism is more complex,so this article elaborates on the research progress of the mechanism of action of traditional Chinese medicine in the treatment of CAG to provide evidence support and new treatment ideas for the treatment of CAG,the intervention of"inflammatory cancer transformation",and the reversal of precancerous lesions by traditional Chinese medicine.
作者
徐璐
王渝涵
李非凡
阳正国
XU Lu;WANG Yu-han;LI Fei-fan;YANG Zheng-guo(Yongchuan Hospital of Traditional Chinese Medicine,Chongqing Medical University,Chongqing 402160;College of Acupuncture and Tuina,Chengdu University of Traditional Chinese Medicine,Chengdu,Sichuan 610075;Yang Zhengguo Inheritance Workshop of Famous Elderly Traditional Chinese Medicine Practitioner,Yongchuan Hospital of Traditional Chinese Medicine/Chongqing,Chongqing 402160)
出处
《中医康复》
2024年第4期39-43,共5页
Traditional Chinese Medicine Rehabilitation
基金
重庆市永川区自然科学基金项目(2022yc-jckx20046):蒲藤护胃汤治疗慢性萎缩性胃炎的临床研究,负责人:阳正国。
关键词
慢性萎缩性胃炎
中医药
炎癌转化
chronic atrophic gastritis
traditional Chinese medicine
inflammatory cancer transformation
