摘要
目的探讨经颅多普勒发泡试验(c-TCD)联合经胸超声心动图声学造影(c-TTE)在筛查卵圆孔未闭(PFO)所致隐源性脑卒中(CS)的临床价值。方法169例CS患者均行c-TCD及c-TTE检查,分析c-TCD、c-TTE单独及联合对于PFO及阳性检出情况、对PFO的诊断效能及下右向左分流(RLS)分级情况的作用。结果与c-TCD比较,联合检测的静息阳性率升高(P<0.05),与c-TTE比较,联合检测的静息阳性率及Valsalva阳性率均升高(P<0.05)。联合诊断PFO的灵敏度及特异度均高于c-TCD、c-TTE单独诊断(P<0.05)。与c-TCD比较,联合检测对RLS 0级、I级的检出率降低,对RLSⅡ级、Ⅲ级的检出率升高(P<0.05),与c-TTE比较,联合检测对RLSⅢ级的检出率升高(P<0.05)。结论c-TCD联合c-TTE能够提高CS患者的PFO及PFO-RLS中大量分级的检出率,提高对PFO的诊断效能。
Objective To explore the clinical value of transcranial Doppler foam test(c-TCD)combined with transthoracic echocardiography contrast acoustics(c-TTE)in screening for cryptogenic stroke(CS)caused by patent foramina ovale(PFO).Methods One hundred and sixty-nine with CS underwent the examination of c-TCD and c-TTE.The role of c-TCD and c-TTE alone and in combination on PFO positive detection and diagnostic efficacy of PFO as well as right-to-left shunt(RLS)levels was analyzed.Results Compared with c-TCD,the resting positive rate of the combination detection was higher(P<0.05).Compared with c-TTE,both resting and Valsalva positive rates of the combination detection were higher(P<0.05).The sensitivity and specificity of combined diagnosis of PFO were higher than that of c-TCD and c-TTE alone(P<0.05).Compared with c-TCD,the detection rate of RLS 0 and I levels was decreased while the detection rate of RLSⅡandⅢlevels was increased(P<0.05).Compared with c-TTE,the detection rate of RLSⅢlevel by the combination detection was increased(P<0.05).Conclusions c-TCD combined with c-TTE diagnosis can improve the detection rate of PFO in CS patients and the detection rate of middle to high levels of PFO-RLS.It also improves the diagnostic efficiency of PFO.
作者
张珍
杜敢琴
段利科
ZHANG Zhen;DU Gan-qin;DUAN Li-ko(Neurology Department,The First Affiliated Hospital,Henan University of Science and Technology,Luoyang 450052,China;Ultrasound Department,The First Affiliated Hospital,Henan University of Science and Technology,Luoyang 450052,China)
出处
《实用医院临床杂志》
2024年第2期90-94,共5页
Practical Journal of Clinical Medicine
基金
河南省重大科技专项立项项目(编号:221100210500)。
关键词
卵圆孔未闭
隐源性脑卒中
经颅多普勒发泡试验
经胸超声心动图声学造影
右向左分流
诊断
Patent foramen ovale
Cryptogenic stroke
Transcranial Doppler foam test
Transthoracic echocardiography echocardiography
Right-to-left shunt
Diagnosis
