摘要
目的 通过倾向性评分匹配分析单纯型乳腺黏液癌超声特征,提高对其诊断准确率。方法 回顾性纳入佛山市第一人民医院在2019年3月~2022年8月术后病理为单纯型乳腺黏液癌的女性患者47例(年龄54.6±14.5岁)作为研究对象,并收集同期手术病理为乳腺纤维腺瘤的患者550例(年龄38.8±9.7岁)作为对照组。采用倾向性评分匹配分析调整基线差异,比较单纯型乳腺粘液癌组和乳腺纤维腺瘤组的临床特征、超声特征和BI-RADS分类。结果 倾向性评分匹配后两组患者年龄、肿物大小、肿物位置比较差异均无统计学意义(P>0.05)。单纯型乳腺黏液癌组肿物表现为无包膜、边缘不光整、内部以实性低回声或混合回声为主、肿物内部有血供,与乳腺纤维腺瘤组相比差异有统计学意义(P<0.05)。单纯型乳腺粘液癌组BI-RADS 4类及以上有87.2%(41/47),而乳腺纤维腺瘤组仅为61.7%(29/47),单纯型乳腺黏液癌组BI-RADS 4类及以上发生率高于乳腺纤维腺瘤组(P=0.005)。单纯型乳腺黏液癌组超声提示5例腋窝淋巴结转移,最后均得到病理证实。结论 根据BI-RADS词典,部分超声征象有助于及早识别单纯型乳腺黏液癌,避免误诊,从而为临床个性化治疗及评估患者预后情况提供依据。
Objective To explore the sonographic features in pure mucinous breast carcinoma(PMBC)by propensity score matching analysis.Methods Fourty-seven female patients(age at 54.6±14.5 years old)with PMBC were retrospectively enrolled in the First People's Hospital Foshan from March 2019 to August 2022 as the research object,and 550 patients(average age 38.8±9.7 years)with breast fibroadenoma(BF)were enrolled as the control group in the same time.The propensity score matching analysis was performed to adjust the baseline differences,and the clinical characteristics,sonographic features and BI-RADS category were compared between the PMBC and BF groups.Results There was no significant difference in age,tumor size and tumor location between the two groups after propensity score matching(P>0.05).Absence of tumor capsule,not circumscribed tumor margin,mixed echoic with cystic and solid component,and internal blood flow were significantly more frequent in PMBC group than in BF group(P<0.05).The incidence of BI-RADS category 4 or above was 87.2%(41/47)and 61.7%(29/47)in PMBC and BF group,respectively.The incidence of BI-RADS category 4 or above was significantly higher in PMBC group than BF group(P=0.005).Five cases with axillary lymph node metastasis confirmed by pathology were detected on ultrasound in PMBC group.Conclusion The sonographic features can help early identification of PMBC and avoid misdiagnosis,so as to provide basis for clinical personalized treatment and evaluation of patient prognosis.
作者
方芹
黄伟俊
叶洁仪
邱懿德
何艳萍
纪晓丹
方洁莹
FANG Qin;HUANG Weijun;YE Jieyi;QIU Yide;HE Yanping;JI Xiaodan;FANG Jieying(Department of Medical Ultrasound,the First People's Hospial of Foshan,Foshan 528000,China)
出处
《分子影像学杂志》
2024年第2期201-205,共5页
Journal of Molecular Imaging
基金
佛山市“十四五”医学高水平重点专科建设项目(FSGSP145037)。
