摘要
慢性乙型肝炎(chronic hepatitis B,CHB)是全球性的公共卫生问题,我国是CHB危害最为严重的国家之一。母婴传播是乙肝病毒(hepatitis B virus,HBV)感染的重要途径,治疗和阻断孕期HBV传播是降低HBV感染及CHB患病率的重要手段。本文从妊娠期CHB的治疗现状入手,综述了国内外妊娠期CHB抗病毒治疗药物、治疗病毒载量阈值及治疗时机选择,并对妊娠期CHB的治疗新希望提出展望。
Chronic hepatitis B(CHB)is a global public health problem,and China is one of the countries with the most severe harm from CHB.Maternal-infant transmission is an important cause of hepatitis B virus(HBV)infection.Treatment and interruption of HBV trans⁃mission during pregnancy are important means to reduce HBV infection and the prevalence of CHB.This article starts with the current treatment status of gestational CHB,reviews the antiviral treatment drugs,viral load thresholds,and treatment timing for gestational CHB at home and abroad,and proposes bold prospects for new treatment prospects for gestational CHB.
作者
赵阳
王玉茹
夏萍
方爽
马福成
金芳多
赵臣
ZHAO Yang;WANG Yuru;XIA Ping;FANG Shuang;MA Fucheng;JIN Fangduo;ZHAO Chen(The 965th Hos-pital of the Joint Logistics Support Force of the People's Liberation Army of China,Jilin City,Jilin Province 132012;School of Public Health,Jilin Medical College,Jilin City,Jilin Province 132013,China)
出处
《吉林医药学院学报》
2024年第2期131-135,共5页
Journal of Jilin Medical University
基金
吉林省科技发展计划重点研发项目(20230203088SF)。
关键词
慢性乙型肝炎
乙肝病毒
妊娠期
抗病毒治疗
垂直传播
chronic hepatitis B
hepatitis B virus
pregnancy period
antiviral therapy
vertical transmission
