摘要
目的探讨胸腔镜肺叶切除患者术后肺部感染病原菌及其危险因素.方法选择2019年1月—2022年12月于成都大学附属医院实施胸腔镜肺叶切除术治疗的肺癌患者327例为研究对象,并根据术后肺部感染情况分为感染组(n=38)和未感染组(n=289),分析感染组患者肺部病原菌情况,归纳胸腔镜肺叶切除患者术后肺部感染的危险因素.结果肺部感染患者总共培养分离病原菌54株,其中革兰阳性菌22株占40.74%,革兰阴性菌28株占51.85%,真菌4株占7.41%,以铜绿假单胞菌、肺炎克雷伯菌以及金黄色葡萄球菌为主;糖尿病(OR=1.880)、慢性阻塞性肺病(OR=2.343)、手术时间(OR=2.161)是胸腔镜肺叶切除患者术后肺部感染的危险因素(P<0.05).结论糖尿病、慢性阻塞性肺病、手术时间是胸腔镜肺叶切除患者术后肺部感染的危险因素,且感染病原菌以革兰阴性菌为主,临床应针对高危人群及感染病原菌种类进行有效预防和治疗.
OBJECTIVE To investigate the postoperative infectious pathogens in patients undergoing thoracoscopic lobectomy and their rick factors.METHODS Totally 327 lung cancer patients who underwent thoracoscopic lobec-tomy at the Affiliated Hospital of Chengdu University from Jan.2019 to Dec.2022 were selected as the study subjects,and they were divided into the infection group(n=38)and the non-infection group(n=289)according to postoperative pulmonary infection,and the lung pathogens in the patients of the infection group were analyzed,and the risk factors of postoperative pulmonary infection in patients undergoing thoracoscopic lobectomy were summarized.RESULTS A total of 54 strains of pathogenic bacteria were cultured and isolated from patients with pulmonary infections,of which 22 strains of gram positive bacteria accounted for 40.74%,28 strains of Gram negative bacteria accounted for 51.85%,and 4 strains of fungi accounted for 7.41%,with Pseudomonas aerugi-nosa,Klebsiella pneumoniae,and Staphylococcus aureus being the predominant strains.The combination of dia-betes mellitus(OR=1.880),chronic obstructive pulmonary disease(OR=2.343),and the duration of operation(OR=2.161)were risk factors for postoperative pulmonary infection in patients undergoing thoracoscopic lobec-tomy(P<0.05).CONCLUSION Diabetes mellitus,chronic obstructive pulmonary disease,and duration of oper-ation were risk factors for postoperative pulmonary infection in patients undergoing thoracoscopic lobectomy,and the infectious bacteria were mainly gram-negative bacteria.Clinical prevention and treatment should be targeted for the high-risk groups and the type of infectious pathogens.
作者
刘丽
樊新星
苏东辉
熊健
LIU Li;FAN Xin-xing;SU Dong-hui;XIONG Jian(Affiliated Hospital of Chengdu University,Chengdu,Sichuan 61008l,China;不详)
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2024年第4期538-541,共4页
Chinese Journal of Nosocomiology
基金
四川省医学会基金资助项目(2022SAT02)。
关键词
胸腔镜肺叶切除术
病原菌
肺部感染
术后感染
危险因素
Thoracoscopy lobectomy
Pathogenic bacteria
Pulmonary infection
Postoperative infection
Risk factor
