摘要
目的探究颅脑CT灌注成像相关指标与IMT在评估短暂性脑缺血发作(TIA)进展为急性脑梗死中的应用价值。方法收集2021年6月-2023年6月于我院治疗的102例TIA患者临床资料。依照是否发生急性脑梗死分为脑梗死的观察组和非脑梗死的对照组。比较2组一般资料、颅脑CT灌注成像相关指标、IMT;颅脑CT灌注成像相关指标与IMT对短暂性脑缺血发作患者急性脑梗死的预测价值;分析颅脑CT灌注成像相关指标与IMT的相关关系。结果两组年龄、性别、高血脂、糖尿病、高血压比较差异无统计学意义(P>0.05)。观察组CBV、CBF均低于对照组,MTT、Tmax均高于对照组,差异显著,(P<0.05)。观察组IMT高于对照组,差异显著,(P<0.05)。颅脑CT灌注成像相关指标与IMT对短暂性脑缺血发作患者进展为急性脑梗死的预测价值良好,AUC为0.886,P=0.000,特异度、灵敏度较高,分别为0.904、0.846。CBV、CBF、MTT、Tmax、IMT的阈值分别为3.326ml/100g、33.682ml/min·100g、9.840s、12.562s、1.082mm。颅脑CT灌注成像相关指标CBV、CBF与短暂性脑缺血发作患者IMT呈负相关关系,MTT、Tmax与短暂性脑缺血发作患者IMT呈正相关关系,差异显著,(P<0.05)。结论颅脑CT灌注成像相关指标与IMT对短暂性脑缺血发作患者进展为急性脑梗死有良好的预测价值。颅脑CT灌注成像相关指标与IMT有显著相关性。
Objective To explore the application value of cerebral CT perfusion imaging and IMT in evaluating the progression of transient ischemic attack(TIA)to acute cerebral infarction.Methods The clinical data of 102 patients with TIA treated in our hospital from June 2021 to June 2023 were collected.According to whether acute cerebral infarction occurred,the patients were divided into cerebral infarction observation group and noncerebral infarction control group.General data,cerebral CT perfusion imaging and IMT were compared between the two groups.Prognostic value of cerebral CT perfusion imaging and IMT for acute cerebral infarction in patients with transient ischemic attack;The correlation between cerebral CT perfusion imaging and IMT was analyzed.Results There was no significant difference in age,sex,hyperlipidemia,diabetes and hypertension between the two groups(P>0.05).The CBV and CBF of the observation group were lower than those of the control group,and the MTT and Tmax were higher than those of the control group,the differences were significant(P<0.05).The IMT in the observation group was significantly higher than that in the control group(P<0.05).The correlation indexes of cerebral CT perfusion imaging and IMT had good predictive value for the progression to acute cerebral infarction in patients with transient ischemic attack(AUC was 0.886,P=0.000),and the specificity and sensitivity were high(0.904 and 0.846,respectively).The thresholds of CBV,CBF,MTT,Tmax,and IMT are 3.326ml/100g,33.682ml/min·100g,9.840s,12.562s,and 1.082mm,respectively.CBV and CBF of cerebral CT perfusion imaging were negatively correlated with IMT of transient ischemic attack patients,while MTT and Tmax were positively correlated with IMT of transient ischemic attack patients,the difference was significant(P<0.05).Conclusion Cerebral CT perfusion imaging and IMT have good predictive value in patients with transient ischemic attack progressing to acute cerebral infarction.There was significant correlation between cerebral CT perfusion imaging and IMT.
作者
郭艳利
胡示超
秦文宇
GUO Yan-li;HU Shi-chao;QIN Wen-yu(CT Room of Hebi People's Hospital,Hebi 458030,Henan Province,China)
出处
《罕少疾病杂志》
2024年第3期19-21,共3页
Journal of Rare and Uncommon Diseases
关键词
颅脑CT灌注成像
短暂性脑缺血
IMT
预测
相关性
Cerebral CT Perfusion Imaging
Transient Cerebral Ischemia
IMT
Forecast
Correlation
