摘要
目的 探讨在癌症患者中使用双源CT结合低流速和低管电压方案的可行性。方法 共纳入90名进行上腹部增强CT扫描的患者,并随机分为A组、B组和C组(每组30人)。在A组中,患者使用120kVp和448mgl/kg对比剂量进行扫描。B组患者以100kVp和336 mgl/kg对比剂量进行扫描。C组患者以70kVp和224mgI/kg对比剂量进行扫描。对CT值、标准差、信噪比、对比噪声比、主观评分、对比剂剂量和流速进行测量。结果 在三组中,除了肾脏外,主观图像评分无统计学差异(均P>0.05)。与其他组相比,C组在大多数感兴趣区域(ROIs)中显示出显著更高的CT值、更低的噪声水平以及更高的SNR和CNR值(P<0.05)。与A组相比,C组所用对比剂剂量减少了47.3%(79.2±13.7 vs.41.7±8.9,P<0.01),对比剂注射速率降低了19.2%(2.6±0.5 vs.2.1±0.4,P<0.01)。结论 在化疗后血管受损的患者中使用70kVp管电压结合高管电流的方法,在保证图像质量和诊断信心的同时降低流速是可行的。
Objective The primary aim of this investigation is to assess the viability of employing dual-source CT in conjunction with reduced tube current and diminished tube voltage for the post-chemotherapeutic evaluation of imaging in oncological patients.MethodsA cohort of 90 individuals undergoing contrast-enhanced CT scans of the upper abdominal region was prospectively enrolled,with random allocation into three groups,denoted as A,B,and C,each comprising 30 subjects.Group A underwent scanning at 120 kVp with a contrast dosage of 448 mgI/kg,Group B at 100 kVp with 336 mgI/kg,and Group C at 70 kVp with 224 mgI/kg.Quantitative assessments encompassed CT attenuation values,standard deviations,signal-to-noise ratios(SNR),contrast-to-noise ratios(CNR),subjective ratings,contrast agent dosages,and flow velocities.Results Excepting renal regions,subjective image evaluations did not manifest statistically significant variances among the three groups(allP>0.05).Group C exhibited notably elevated CT attenuation values,decreased noise levels,and heightened SNR and CNR values across a majority of regions of interest(ROIs)relative to the comparator groups(P<0.05).In contrast to Group A,Group C demonstrated a substantial 47.3%reduction in contrast agent dosage(79.2±13.7 vs.41.7±8.9,P<0.01)and a 19.2%decrease in contrast injection rate(2.6±0.5 vs.2.1±0.4,P<0.01).ConclusionThe application of a 70 kVp tube voltage combined with heightened tube current subsequent to chemotherapy-induced vascular impairment proves to be a feasible strategy.This approach concurrently achieves a reduction in flow velocity while upholding imaging quality and diagnostic confidence.
作者
刘杰
张怡存
李林峰
原典
齐珂
张梦圆
张炜珽
魏楠楠
高剑波
吕培杰
LIU Jie;ZHANG Yi-cun;LI Lin-feng;YUAN Dian;Qi Ke;ZHANG Meng-yuan;ZHANG Wei-ting;WEI Nan-nan;Gao Jian-bo;LV Pei-jie(Department of Radiology,The First Affiliated Hospital of Zhengzhou University,Zhengzhou 450000,Henan Province,China;CT collaboration,Siemens Healthineers Digital Technology(Shanghai)Co.,Ltd.,Shanghai 200000,China)
出处
《中国CT和MRI杂志》
2024年第3期119-122,共4页
Chinese Journal of CT and MRI
基金
河南省卫生健康委员会科技攻关项目(No.212102310142)。
关键词
低流速
低管电压
低对比剂剂量
高管电流
上腹部CT
Low Flow Rate
Low Tube Voltage
Low Contrast Agent
High Tube Current
Upper-abdomen Enhanced CT
