摘要
目的:观察揿针治疗亚急性甲状腺炎的临床疗效。方法:将110例亚急性甲状腺炎患者按照随机数字表法分为治疗组和对照组,每组各55例。对照组给予口服双氯芬酸钠缓释片治疗,治疗组在对照组治疗的基础上给予揿针治疗,不服用醋酸泼尼松片。观察两组患者治疗前后中医证候积分、减分率、甲状腺肿痛消失时间、血沉恢复正常时间、甲状腺摄碘率恢复正常时间、血清淀粉样蛋白A(serum amyloid A,SAA)、肿瘤坏死因子(tumor necrosis factor,TNF)-β、白细胞介素(interleukin,IL)-6及临床疗效、1年后复发率。结果:治疗组治疗后中医证候积分低于对照组,差异有统计学意义(P<0.05)。治疗组中医证候积分减分率为71.1%,对照组中医证候积分减分率为36.7%,治疗组高于对照组,差异有统计学意义(P<0.05)。治疗组治疗后SAA、TNF-β、IL-6水平低于对照组,差异有统计学意义(P<0.05)。治疗组治疗后甲状腺肿痛消失时间、血沉恢复正常时间、甲状腺摄碘率恢复正常时间短于对照组,差异有统计学意义(P<0.05)。治疗组有效率为100%,1年后复发率为3.6%,对照组有效率为90.9%,1年后复发率为16.4%,治疗组有效率高于对照组,1年后复发率低于对照组,差异有统计学意义(P<0.05)。结论:揿针治疗亚急性甲状腺炎,可以更快缓解患者临床症状,改善中医证候,降低SAA、TNF-β、IL-6水平和复发率。
Objective:To observe the clinical efficacy of acupuncture with thumbtack needle on subacute thyroiditis(SAT).Methods:A total of 110 patients with SAT were divided into the treatment group and the control group according to the random number table method,with 55 cases in each group.The control group was given Diclofenac Sodium Sustained-Release Tablets for oral administration,while the treatment group was given acupuncture with thumbtack needle on the basis of the control group,without taking Prednisone Acetate Tablets.The TCM syndrome scores,score reduction rate,thyroid swelling pain disappearing time,erythrocyte sedimentation rate normal time,thyroid iodine uptake rate returning to normal time,serum amyloid A(SAA),tumor necrosis factor(TNF)-β,interleukin(IL)-6,clinical efficacy and recurrence rate after one year were observed in the two groups before and after treatment.Results:After treatment,the TCM syndrome scores of the treatment group were lower than those of the control group,with statistically significant differences(P<0.05).The score reduction rate of TCM syndrome scores of the treatment group was 71.1%,which was higher than that of the control group(36.7%),with statistically significant difference(P<0.05).The levels of SAA,TNF-β,IL-6 in the treatment group were lower than those in the control group,with statistically significant differences(P<0.05).The disappearance time of thyroid swelling and pain,the recovery time of erythrocyte sedimentation rate and the recovery time of thyroid iodine uptake rate in the treatment group were shorter than those in the control group,with statistically significant differences(P<0.05).The effective rate of the treatment group was 100%,and the recurrence rate was 3.6% after one year.The effective rate of the control group was 90.9%,and the recurrence rate was 16.4% after one year.The effective rate of the treatment group was higher than that of the control group,while the recurrence rate after one year was lower than that of the control group,with statistically significant differences(P<0.05).Conclusion:Acupuncture with thumbtack needle in the treatment of SAT can relieve the clinical symptoms of patients more quickly,improve the TCM syndromes,reduce the levels of SAA,TNF-β,IL-6 and the recurrence rate.
作者
冯臻谛
梁静华
冯胜奎
翟煦
FENG Zhendi;LIANG Jinghua;FENG Shengkui;ZHAI Xu(Wangjing Hospital of CACMS,Beijing,China,100102;Guangwai Hospital of Xicheng District of Beijing,Beijing,China,100055;Institute of Acupuncture and Moxibustion,China Academy of Chinese Medical Sciences,Beijing,China,100700)
出处
《河南中医》
2024年第3期433-438,共6页
Henan Traditional Chinese Medicine
关键词
亚急性甲状腺炎
揿针
双氯芬酸钠缓释片
subacute thyroiditis(SAT)
acupuncture with thumbtack needle
Diclofenac Sodium Sustained-Release Tablets
