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中药蟾酥的质量研究现状

Quality research status of Chinese medicine Toad venom
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摘要 蟾酥是蟾蜍科动物中华大蟾蜍或黑眶蟾蜍的耳后腺或皮肤腺体的干燥分泌物。蟾酥作为一种传统的中药,化学成分复杂,临床用途较广,具有抗肿瘤、强心、抗炎、局麻、镇痛等多种药理活性。本文从蟾酥的本草考证、质量影响因素和质量标准现状等方面总结了蟾酥质量研究现状,以期从现行标准出发,为蟾酥药材的进一步质量控制提供参考。 Toad venom is a dry secretion from the posterior auricular glands or skin glands of the Bufonidae,Bufo bufo gargarizans Cantor,or Bufo melanostictus Schneider.As a traditional Chinese medicine,Toad venom has a complex chemical composition and wide clinical application.It has many pharmacological activities,such as anti-tumor,cardiac strengthening,anti-inflammatory,local anesthesia,alleviating pain,and so on.This paper summarizes the research status of the quality of Toad venom from the aspects of herbalogical study,quality influencing factors,and quality standards.It is expected to provide a reference for the further quality control of Toad venom medicinal materials from the current standards.
作者 石丽 焦阳 薛菲 陈娟 汪冰 林永强 SHI Li;JIAO Yang;XUE Fei;CHEN Juan;WANG Bing;LIN Yongqiang(NMPA Key Laboratory for Quality Evaluation of Gelatin Products,Shandong Engineering Research Center for Traditional Chinese Medicine Standard Innovation and Quality Evaluation,Shandong Engineering Research Center of Generic Technologies for Traditional Chinese Medicine Formula Granules,Shandong Institute for Food and Drug Control,Jinan 250101,China;Shandong University of Traditional Chinese Medicine,Jinan 250355,China)
出处 《药学研究》 CAS 2024年第2期171-177,共7页 Journal of Pharmaceutical Research
基金 山东省重点研发计划重大科技创新工程项目(No.2021CXGC010511) 国家重点研发计划(中医药现代化)课题(No.2023YFC3504102)。
关键词 蟾酥 本草考证 影响因素 分析技术 质量标准 Toad venom Herbalogical study Influence factor Analysis technics Quality standards
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