摘要
目的探究微血管成像(SMI)分级及CT血管造影(CTA)联合血清小而密低密度脂蛋白胆固醇(sdLDL-C)对老年高血压伴急性脑梗死(ACI)的诊断价值。方法选取2021年6月至2023年6月苏州市第九人民医院收治的老年高血压患者180例,根据患者ACI发生情况分为ACI组95例和非ACI组85例。比较2组SMI分级、CTA、血清sdLDL-C水平,ROC曲线分析SMI分级及CTA联合血清sdLDL-C对高血压患者发生ACI的诊断价值,多因素logistic回归分析影响高血压患者发生ACI的因素。结果ACI组血脂异常、舒张压、收缩压、高密度脂蛋白胆固醇、低密度脂蛋白胆固醇高于非ACI组(P<0.01)。ACI组血清sdLDL-C水平高于非ACI组[(1.62±0.25)mmol/L vs(1.35±0.19)mmol/L,P<0.01],ACI组和非ACI组SMI分级比较,差异有统计学意义(P<0.01)。ROC曲线分析显示,SMI分级和CTA及血清sdLDL-C三者联合诊断高血压患者发生ACI的曲线下面积为0.934(95%CI:0.897~0.972)。多因素logistic回归分析显示,SMI分级、CTA、sdLDL-C是高血压患者发生ACI的危险因素(P<0.01)。结论SMI分级及CTA联合血清sdLDL-C对老年高血压伴ACI有较高的辅助诊断价值。
Objective To investigate the diagnostic value of superb microvascular imaging(SMI)grading,CT angiography(CTA),and serum small and dense low-density lipoprotein cholesterol(sdLDL-C)in elderly hypertension patients with acute cerebral infarction(ACI).Methods A retrospective study was conducted on 180 elderly hypertension patients admitted to our hospital from June 2021 to June 2023,and those admitted due to ACI were assigned into ACI group(95 cases)and those without into non-ACI group(85 cases).The SMI grade,CTA,and serum sdLDL-C level were compared between the two groups.ROC curve was plotted to analyze the diagnostic value of SMI grading and CTA combined with serum sdLDL-C for ACI in patients with hypertension.Multivariate logistic regression analysis was employed to analyze the factors affecting the occurrence of ACI in the patients.Results The ACI group had significantly larger proportion of hyperlipidemia,and higher DBP,SBP,and HDL-C,and LDL-C than the non-ACI group(P<0.05).The proportion of SMI grade 2 and grade 3 and serum sdLDL-C level were also greatly higher[35.79%vs 10.59%,43.16%vs 8.24%,(1.62±0.25)mmol/L vs(1.35±0.19)mmol/L,P<0.01],and the proportion of SMI grade 0 and grade 1 was lower(11.58%vs 51.76%,9.47%vs 29.41%,P<0.01)in the ACI group than the non-ACI group.ROC curve analysis showed that the AUC value of SMI grade and CTA combined with serum sdLDL-C in diagnosing ACI in patients with hypertension was 0.934(95%CI:0.897-0.972).Multivariate logistic regression analysis indicated that SMI grade,CTA,and sdLDL-C were risk factors for ACI in hypertensive patients(P<0.01).Conclusion Combination of carotid artery plaque SMI grading,CTA,and serum sdLDL-C has high auxiliary diagnostic value for elderly hypertension patients with ACI.
作者
徐卫华
计玉芳
陆赵阳
徐敏
Xu Weihua;Ji Yufang;Lu Zhaoyang;Xu Min(Department of Ultrasonography,Suzhou Ninth People's Hospital,Suzhou 215000,Jiangsu Province,China)
出处
《中华老年心脑血管病杂志》
CAS
北大核心
2024年第2期188-191,共4页
Chinese Journal of Geriatric Heart,Brain and Vessel Diseases
关键词
计算机体层摄影血管造影术
小而密低密度脂蛋白胆固醇
超微血流成像
磁共振血管成像
computed tomography angiography
small and dense low-density lipoprotein cholesterol
superb microvascular imaging
magnetic resonance angiography
