摘要
目的针灸联合内养功治疗慢性盆腔炎对患者盆腔包块直径和子宫动脉血流动力参数的影响。方法将86例慢性盆腔炎患者以1∶1比例随机分为对照组和观察组各43例,对照组予以常规西医基础治疗,观察组在对照组的西医用药基础上加予针灸联合内养功治疗,评估两组治疗1个月经周期后的临床疗效,对比两组治疗前及治疗1个月经周期后的中医症状评分、最大肿块直径、疼痛程度[视觉模拟评分法(VAS)]、子宫动脉血流动力参数[子宫动脉血管搏动指数(PI)和血管阻力指数(RI)、收缩期峰流速度(Vs)]及血清炎症指标[补体C_(3)、单核细胞趋化蛋白-1(MCP-1)及转化生长因子-TGF-β1(TGF-β1)]水平。结果观察组的的临床总有效率显著高于对照组(88.37%vs 69.77%,P<0.05);治疗后,两组关于腹部疼痛、腰部疼痛、白带色黄共3项中医症状评分相比治疗前均有显著性下降(P<0.05),两组的最大肿块直径和VAS评分相比治疗前均显著降低(P<0.05),两组的PI、RI及Vs值均较治疗前有显著性增加(P<0.05),两组的血清补体C_(3)、MCP-1水平较治疗前有显著性降低(P<0.05),血清TGF-β1水平较治疗前有显著性提升(P<0.05),以上指标观察组的变化幅度显著大于对照组(P<0.05);两组不良反应总发生率无显著性差异(P>0.05);观察组疾病复发率显著低于对照组(4.65%vs 18.60%,P<0.05)。结论针灸联合内养功治疗慢性盆腔炎的疗效显著,能明显改善中医相关症状,缩小盆腔包块直径,并减少腰腹痛感,改善子宫动脉血流动力参数,并能纠正机体血清炎症反应,不良反应少,复发率低。
Objective To observe the effect of Huoxue Qianyang Qutan Recipe(活血潜阳祛痰方,HQQR)on myocardial hypertrophy and myocardial mitochondrial function in obese hypertensive rats.Methods Eighty-six patients with chronic pelvic inflammatory disease were randomly divided into control group(43 cases)and observation group(43 cases)in a ratio of 1∶1.The control group was given conventional western medicine basic treatment while the observation group was additionally givenacupuncture and moxibustion combined with intrinsic-nourishing exercise on the basis of western medicine in the control group.The clinical efficacy after 1 menstrual cycle of treatment was evaluated,and the TCM symptoms scores,maximum mass diameter,pain degree[visual analogue scale(VAS)],and uterine artery hemodynamic parameters[uterine artery pulsatility index(PI),vascular resistance index(RI),peak systolic flow velocity(Vs)]and serum inflammatory indicators[complement C_(3),monocyte chemoattractant protein-1(MCP-1),transforming growth factor-TGF-β1(TGF-β1)]were compared between the two groups before treatment and after 1 menstrual cycle of treatment.Results The clinical total effective rate of observation group was significantly higher than that of control group(88.37%vs 69.77%,P<0.05).After treatment,the scores of three TCM symptoms such as abdominal pain,waist painand leucorrhea with yellow color in the two groups were significantly decreased compared with those before treatment(P<0.05),and the maximum mass diameter and VAS score of both groups were significantly reduced(P<0.05)while the PI,RI and Vs were significantly enhanced(P<0.05),and the levels of serum complement C_(3) and MCP-1of the two groups were significantly lower than those before treatment(P<0.05)while the level of serum TGF-β1 was significantly higher than that before treatment(P<0.05),and the changes of the above indicators in observation group were significantly greater than those in control group(P<0.05).There was no significant difference in the total incidence rate of adverse reactions between the two groups(P>0.05).The disease recurrence rate in observation group was significantly lower than that in control group(4.65%vs 18.60%,P<0.05).Conclusion Acupuncture and moxibustion combined with intrinsic-nourishing exercise has a significant efficacy on chronic pelvic inflammatory disease,and it can significantly improve TCM-related symptoms,reduce the diameter of pelvic mass,relieve waist pain and abdominal pain and improve uterine artery hemodynamic parameters,and can correct the body’s serum inflammatory response,and it has few adverse reactions and low recurrence rate.
作者
杨春香
邸志芳
刘新
肖远德
YANG Chunxiang;DI Zhifang;LIU Xin;XIAO Yuande(Department of Rehabilitation,Hebei Rehabilitation Hospital,Qinhuangdao 066000,Hebei,China)
出处
《辽宁中医杂志》
CAS
北大核心
2024年第1期183-187,共5页
Liaoning Journal of Traditional Chinese Medicine
基金
国家自然科学基金(81774111)
中医重点专科培育项目:上海市进一步加快中医药事业发展三年行动计划(2018—2020年)-中医心病专科。
关键词
慢性盆腔炎
针灸
内养功
盆腔包块直径
子宫动脉血流动力参数
Chronic pelvic inflammatory disease
Acupuncture and moxibustion
Intrinsic-nourishing exercise
Pelvic mass diameter
Uterine artery hemodynamic parameters
