摘要
肾纤维化是许多肾脏疾病的最终转归,因此,延缓肾纤维化过程对肾脏疾病的治疗尤为重要。CD248是一种Ⅰ型跨膜糖蛋白,在肾纤维化中表达上调,通过敲除CD248可抑制肾纤维化,这表明CD248在肾纤维化过程中可能起到重要作用。该文将对CD248在肾脏疾病中的相关作用进行综述。
Renal fibrosis is the final outcome of many renal diseases,so delaying the process of renal fibrosis is particularly important for the treatment of renal diseases.CD248 is a type I transmembrane glycoprotein,which is up-regulated in renal fibrosis.The knockdown of CD248 can inhibit renal fibrosis,suggesting that CD248 may play an important role in the process of renal fibrosis.This article will review the relevant roles of CD248 in renal diseases.
作者
卢欣节
尤燕舞
LU Xinjie;YOU Yanwu(Graduate School,Youjiang Medical University for Nationalities,Baise 533000,Guangxi,China;Department of Nephrology,Guangxi Academy of Medical Sciences·the People's Hospital of Guangxi Zhuang Autonomous Region,Nanning 530000,Guangxi,China)
出处
《右江医学》
2024年第2期97-102,共6页
Chinese Youjiang Medical Journal
基金
广西自然科学基金(2023GXNSFAA026005)。
