摘要
目的探究经颅磁刺激联合醒脑开窍针对脑卒中患者神经功能及认知功能的影响。方法选取76例脑卒中患者,随机分为治疗组与对照组各38例。两组均接受常规对症处理,在此基础上,治疗组予以经颅磁刺激联合醒脑开窍针治疗,而对照组仅予经颅磁刺激治疗,两组均治疗6周。分别于治疗前后进行神经递质指标[P物质(SP)、神经肽Y(NPY)、5-羟色胺(5-HT)]水平检测,并记录神经功能、认知功能、日常生活能力以及中医证候积分,同时于疗程结束后评价临床疗效并观察不良反应。结果治疗后,治疗组的总有效率高于对照组(P<0.05),而组间不良事件则未见显著差异(P>0.05)。两组各项中医证候积分、NIHSS评分以及SP、NPY水平均明显降低,且治疗组较对照组更低(P<0.01)。两组MoCA、BI评分以及5-HT水平均明显升高,且治疗组较对照组更高(P<0.01)。结论经颅磁刺激联合醒脑开窍针能够显著改善脑卒中患者的神经功能和认知功能,并对神经递质含量具有良好调节作用,疗效显著且安全性高。
Objective:To explore the effect of transcranial magnetic stimulation combined with Xingnao Kaiq⁃iao Acupuncture on neurological and cognitive function in stroke patients.Methods:A total of 76 stroke patients who were treated in our hospital were selected and randomly divided into treatment group(38 cases)and control group(38 cases).Both groups received routine symptomatic treatment.On this basis,the treatment group was treat⁃ed with transcranial magnetic stimulation combined with Xingnao Kaiqiao Acupuncture,while the control group was only treated with transcranial magnetic stimulation.Both groups were treated for 6 weeks.The levels of neu⁃rotransmitter indicators[Substance P(SP),Neuropeptide Y(NPY),5-hydroxytryptamine(5-HT)]were detected before and after treatment,and the neurological function,cognitive function,ability of daily living and traditional Chinese medicine(TCM)syndrome score were recorded.At the same time,the clinical efficacy was evaluated,and the adverse reactions were observed after the treatment.Results:After treatment,the total effective rate of the treatment group was higher than that of the control group(P<0.05),while there was no significant difference in ad⁃verse events between the groups(P>0.05).The scores of various TCM syndromes,NIHSS scores,and SP and NPY levels in both groups were significantly reduced,and the treatment group were lower than the control group(P<0.01).The MoCA,BI scores,and 5-HT levels were significantly increased in both groups,and the treatment group was higher than the control group(P<0.01).Conclusion:Transcranial magnetic stimulation combined with Xing⁃nao Kaiqiao Acupuncture can significantly improve the neurological and cognitive functions of stroke patients,and has a good regulatory effect on neurotransmitter content.The overall treatment effect is significant and safe.
作者
金倩倩
俞红
王哈妮
Jin Qianqian;Yu Hong;Wang Hani(Zhejiang Rehabilitation Medical Center Rehabilitation Evaluation and Treatment Center,Zhejiang,Hangzhou 310051,China)
出处
《中国中医急症》
2024年第3期465-468,共4页
Journal of Emergency in Traditional Chinese Medicine
基金
浙江省中医药科技计划项目(2023ZL129)。
关键词
脑卒中
经颅磁刺激
针刺
醒脑开窍针
神经功能
认知功能
Stroke
Transcranial magnetic stimulation
Acupuncture
Xingnao Kaiqiao Acupuncture
Neurologi⁃cal function
Cognitive function
