摘要
强迫症是一种常见的高致残性精神障碍,伴随多种认知功能的缺陷。其中,反应抑制缺陷可能是强迫症的一种潜在的内表型,对于理解强迫症的病理生理机制和开发新的临床治疗方法具有重要意义。本文综述了强迫症反应抑制缺陷及其神经机制和临床干预效果,以期为进一步理解强迫症反应抑制缺陷和促进强迫症的临床诊疗提供依据。
Obsessive-compulsive disorder(0CD)is a prevalent and profoundly debilitating mental disorder characterized by various cognitive impairments.Among them,deficiency in response inhibition may be a potential endophenotype,playing a critical role in comprehending the underlying pathophy siological mechanisms of OCD and facilitating the development of novel clinical treatment approaches.This article reviews the response inhibition defi-cit in OCD,including its neural mechanisms and the effects of clinical interventions,in order to provide evidence for further understanding of the response inhibition deficit in OCD and promote the clinical diagnosis and treatment of OCD.
作者
张晨
范青
ZHANG Chen;FAN Qing(Shanghai Mental Health Center,Shanghai Jiao Tong University School of Medicine,Shanghai 200030,China)
出处
《中国心理卫生杂志》
CSCD
北大核心
2024年第4期306-311,共6页
Chinese Mental Health Journal
基金
国家自然科学基金面上项目(81771460)
上海交通大学“交大之星”计划医工交叉研究基金重点项目(YG2021ZD28)。
关键词
强迫症
反应抑制
额叶-基底神经节模型
综述
obsessive-compulsive disorder
response inhibition
frontal lobe-basal ganglia model
review
