摘要
目的:了解妊娠期BMI轨迹及产后体重滞留(PPWR)与产后1年代谢综合征(MetS)及其各诊断标准之间的关系。方法:选取2019年在南方医科大学附属深圳妇幼保健院分娩的720例产妇进行产后1年随访,内容为问卷、体格检查及实验室检查。采用Spearman秩相关分析不同轨迹亚组及产后体重滞留分组与MetS诊断指标异常数的关系。采用二元logistic回归模型分析不同轨迹亚组及产后体重滞留分组与MetS的相关性。结果:MetS患病率随体重轨迹组从低到高呈逐渐递增。与对照组相比,妊娠期BMI轨迹3的MetS患病风险OR(95%CI)值为6.15(2.81~13.44),PPWR较孕前≥1.85个BMI单位的妇女组患病风险值为3.63(1.10~11.96)。结论:妊娠期BMI轨迹组增高,MetS患病风险越大;产后较产前体重增加超过1.85个BMI单位的妇女患MetS风险增加了2.63倍。
Objective:To investigate the correlation between gestational BMI trajectories,postpartum weight retention(PPWR)and metabolic syndrome(MetS)or diagnostic criteria of Mets at postpartum 1 year.Methods:720 women who delivered in Shenzhen Maternal and Child Healthcare Hospital in 2019 were followed up at 1 year postpartum.The follow-up content included questionnaire,physical examination and laboratory test.Spearman rank correlation was used to analyze the relationship between different trajectory subgroups,PPWR groups and the number of abnormal diagnostic indicators of MetS.Binary logistic regression model was used to analyze the correlation between different trajectory subgroups,PPWR groups and MetS.Results:MetS prevalence increased gradually from low to high in the weight trajectory group.Compared with control group,the OR(95%CI)was 6.15(2.81 to 13.44)in the high pregnancy BMI trajectory group.and 3.63(1.10 to 11.96)for PPWR≥1.85 BMI group.Conclusions:The higher the pregnancy weight trajectory group,the greater the risk of MetS.Women who gained postpartum weight≥1.85 BMI compared to prepregnant weight had a 2.63-fold increased risk of MetS.
作者
张华凡
陈艺璇
吴琳琳
吴晓霞
尹霭琦
胡凤巧
童嘉宁
黄旭娜
万艳梅
牛建民
Zhang Huafan;Chen Yixuan;Wu Linlin(Shenzhen Maternity&Child Healthcare Hospital,The First School of Clinical Medicine,Southern Medical University,Shenzhen 518000;The Eighth Affiliated Hospiatal,Sun Yat-Sen University,Shenzhen 518000)
出处
《现代妇产科进展》
2024年第3期191-195,共5页
Progress in Obstetrics and Gynecology
基金
国家自然科学基金(No:72374227)
深圳市科技计划资助(No:JCYJ20220818103608017)
深圳市科技计划资助(No:JSGG20210802152800001)。
关键词
代谢综合征
妊娠期BMI轨迹
产后体重滞留
潜类别增长模型
Metabolic syndrome
Gestational BMI trajectory
Postpartum weight retention
Latent class growth model
