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基于数字化目诊技术解析高血压的目络特征及与证候要素的相关性

Analysis of the Characteristics of Eye Collateral and Its Correlation with TCM Syndrome Elements in Hypertension Based on Digital Visual Diagnosis Technology
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摘要 目的利用目诊仪研究高血压患者的目络特征并探讨其与中医证候要素的相关性,以期为中医临床探索高血压目络特征、辨证分型提供证据支持。方法纳入高血压患者和健康对照志愿者各263例。目诊仪采集所有受试者的眼白睛图像并进行目络特征的数字化提取,并分析高血压的目络特征与其证候要素之间的相关性。结果与对照组比较,高血压的特征目络形态为“血脉”,特征目络区位为“脾”,特征目络颜色为“黄”“黯黄”“黯”和“黯褐”。高血压的主要证候要素为脾虚。高血压的特征目络形态“血脉”和颜色特征“粉中带黯”与证候要素“脾虚”呈显著负相关。结论采用数字化目诊仪解析高血压的眼象特征并分析其与证候要素的关联性,表明数字化目诊仪可为高血压的临床诊疗提供客观依据和新方法选择,有益于四诊规范化研究和提高疾病防治水平。 Objective Using a visual diagnosis instrument to study the characteristics of eye collateral in hypertension patients and explore its correlation with TCM syndrome elements,in order to provide evidence support for the TCM clinical exploration of the characteristics of eye collateral and syndrome differentiation of hypertension.Methods 263 hypertensive patients and healthy control volunteers were included.The visual instrument collected the white eye images of all subjects,and digitally extracted the eye vein features,then analyzed the correlation between the eye vein features of hypertension and its syndrome elements.Results Compared with the control group,the characteristic morphology of eye collateral in hypertension was"blood vessels",the characteristic eye collateral locations were"liver"and"spleen",and the colors of the characteristic eye collateral were"yellow""dark yellow""dark"and"dark brown".The main syndrome element of hypertension was spleen deficiency.The characteristic morphology of hypertensive eye collateral"blood vessels"and color characteristic of"pink with dark"showed a significant negative correlation with the syndrome element"spleen deficiency".Conclusion Digital visual instrument can analyze the ocular characteristics of hypertension and analyze its correlation with syndrome elements.It shows that the digital visual examination instrument can provide objective basis and new method selection for the clinical diagnosis and treatment of hypertension,and is beneficial to the standardized research of four diagnosis and improve the level of disease prevention and treatment.
作者 刘璇 张琼艺 全虹翰 王雪松 高海英 詹会霞 巩静 朱青 郭姣 LIU Xuan;ZHANG Qiongyi;QUAN Honghan;WANG Xuesong;GAO Haiying;ZHAN Huixia;GONG Jing;ZHU Qing;GUO Jiao(Chinese Medicine Research Institute,Guangdong Pharmaceutical University,Guangzhou 510006,China;The First Affiliated Hospital of Guangdong Pharmaceutical University,Guangzhou 510080,China;Tongji Hospital,Tongji Medical College of HUST,Wuhan 430030,China)
出处 《中国中医基础医学杂志》 CAS CSCD 2024年第3期413-417,共5页 JOURNAL OF BASIC CHINESE MEDICINE
基金 广东省基础研究与应用基础研究重点项目(2018KZDXM042) 国家重点研发计划(2018YFC1704200)。
关键词 高血压 白睛 中医证候 目诊仪 相关性 Hypertension White eye Traditional Chinese medicine syndrome Visual diagnosis instrument Correlation
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