摘要
目的:总结胎儿宫内生长迟缓(IUGR)的危险因素,并探讨其防治措施。方法:选取2021年1月—2022年4月在河南科技大学第二附属医院分娩的109例产妇作为研究对象,开展回顾性研究,统计不同年龄段(低龄、正常育龄、高龄)、不同BMI(偏瘦、正常、偏胖)产妇中IUGR的发生率,根据新生儿是否发生IUGR将产妇分为病例组(55例)和对照组(54例),收集两组产妇临床资料(包括产妇生理因素、精神因素、生活习惯、用药情况、妊娠期合并症、子宫—胎盘血流动力学及血脂代谢功能等)及胎儿相关指标(包括合成代谢功能紊乱、胎盘、脐带等),经单因素、logistic多因素回归分析归纳导致IUGR的危险因素,结合分析结果,提出相应的IUGR防治措施。结果:低龄、偏瘦、妊娠期高血压或糖尿病等合并症、血脂代谢异常、子宫—胎盘血流量低、胎儿宫内感染、大量放射线辐射、胎盘微血栓、脐带结构异常均为IUGR发生的危险因素(OR=2.232、2.614、1.125、2.528、2.049、3.163、0.314、3.662、3.214、0.398,P<0.05)。结论:可导致IUGR发生的危险因素较多,从各种危险因素出发,在分娩前做好产妇相应的干预及护理对防治IUGR具有积极意义。
Objective:To summarize the risk factors for intrauterine growth retardation(IUGR)and to discuss measures for its prevention and treatment.Methods:109 deliveries in hospital from January 2021 to April 2022 were selected for the study,and a retrospective study was conducted.The prevalence of IUGR among women of different ages(low,normal childbearing,high)and different BMI(thin,normal,fat)was counted.Mothers were divided into case group(55 cases)and control group(54 cases)according to whether IUGR occurred in the newborn.Clinical data(including maternal physiological factors,mental factors,living habits,medication use,pregnancy complications,uteroplacental hemodynamics and lipid metabolism function,etc.)and fetal related indexes(including anabolic dysfunction,placenta,umbilical cord,etc.)were collected from the two groups.The risk factors leading to IUGR were summarized by univariate and logistic multifactorial regression analysis,and the corresponding measures for the prevention and treatment of IUGR were proposed in conjunction with the results of the analysis.Results:Low age,low body weight,comorbidities such as hypertension or diabetes mellitus during pregnancy(abnormal lipid metabolism),low utero-placental blood flow,intrauterine fetal infections,high levels of radiation exposure and abnormalities of the placenta(placental microthrombosis)and umbilical cord structure were all risk factors for the development of IUGR(OR=2.232,2.614,1.125,2.528,2.049,3.163,0.314,3.662,3.214,0.398;P<0.05).Conclusion:There are more risk factors that can lead to the occurrence of IUGR,and it is of positive significance to do the appropriate maternal intervention and care before delivery from the perspective of various risk factors to prevent and treat IUGR.
作者
熊艳敏
Xiong Yanmin(Department of Obstetrics,The Second Affiliated Hospital of Henan University of Science and Technology,Luoyang,Henan,471000,China)
出处
《黑龙江医学》
2024年第5期532-535,共4页
Heilongjiang Medical Journal
基金
河南省医学教育研究项目(201900217)。
关键词
胎儿宫内生长迟缓
危险因素
对策
Intrauterine growth retardation
Risk factors
Countermeasures
