Are we close to using Alzheimer blood biomarkers in clinical practice? 被引量：1

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摘要 Alzheimer's disease(AD) is a progressive neurodegenerative disease histologically characterized by the presence of extraneuronal plaques,mainly formed by the 42-aminoacid isoform of amyloid-(Aβ_(1-42)),and by intraneuronal neurofibrillary to ngles,mainly formed by the tau protein and its hyperphosphorylated isoforms(p-tau).AD is the most common cause of dementia,with an estimated lifetime risk of about 1 in 10 for men and 1 in 5 for women.

作者 Bruno P.Imbimbo Simone Lista Camillo Imbimbo Robert Nisticò

机构地区 Department of Research&Development i+HeALTH Strategic Research Group Department of Brain and Behavioral Sciences School of Pharmacy Laboratory of Pharmacology of Synaptic Plasticity

出处《Neural Regeneration Research》 SCIE CAS CSCD 2024年第12期2583-2585,共3页 中国神经再生研究（英文版）

关键词 ALZHEIMER TAU AΒ

分类号 R749.16 [医药卫生—神经病学与精神病学]

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Are we close to using Alzheimer blood biomarkers in clinical practice? 被引量：1

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