摘要
目的探讨血清淀粉酶、脂肪酶及C-反应蛋白联合检验对诊断急性胰腺炎的临床价值。方法选取2020年4月—2022年5月甘肃省天水市第一人民医院收治的50例急性胰腺炎患者为研究组,包括30例轻型急性胰腺炎患者及20例重型急性胰腺炎患者;同时选择50例非急性胰腺炎急腹症患者作为A1组,50例健康体检人员作为A2组;对所有研究对象均展开血清淀粉酶水平检测、脂肪酶水平检测以及C反应蛋白检测,比较3组的血清淀粉酶水平、脂肪酶水平以及C反应蛋白检测结果,比较轻型、重型急性胰腺炎患者指标测定结果,并进行相关性分析。结果研究组血清淀粉酶水平、血清脂肪酶水平及C反应蛋白水平均高于A2组和A1组,差异有统计学意义(P均<0.05);重型急性胰腺炎患者血清淀粉酶水平为(768.49±43.22)U/L、血清脂肪酶水平为(1694.88±300.15)mg/L、C反应蛋白水平为(137.49±13.35)mg/L,高于轻型急性胰腺炎患者的(591.85±48.22)U/L、(1232.49±300.13)mg/L、(26.25±4.13)mg/L,差异有统计学意义(t=19.288、7.702、56.288,P均<0.05)。随着急性胰腺炎病情的严重,患者的血清淀粉酶水平、血清脂肪酶水平以及C反应蛋白水平呈现出显著提升(r=0.128、0.139、0.137,P均<0.05)。结论临床对急性胰腺炎患者在开展早期诊断工作期间,合理展开血清淀粉酶水平、血清脂肪酶水平以及C反应蛋白水平检测工作,可为疾病顺利诊断提供一定依据,发现随着急性胰腺炎病情的严重,患者的血清淀粉酶水平、血清脂肪酶水平以及C反应蛋白水平呈现出显著提升对于疾病的有效治疗可以奠定基础。
Objective To explore the clinical value of the combined test of serum amylase,lipase and C-reactive pro⁃tein for the diagnosis of acute pancreatitis.Methods 50 acute pancreatitis patients admitted to the Tianshui First People's Hospital,Gansu Province from April 2020 to May 2022 were selected as the study group,including 30 pa⁃tients with mild acute pancreatitis and 20 patients with severe acute pancreatitis;at the same time,50 patients with non-acute pancreatitis were selected as A1 group,and 50 healthy examination personnel were selected as A2 group.Serum amylase level,lipase level and C reactive protein were tested for all study subjects,comparing the serum amy⁃lase levels,lipase levels,and the C reactive protein test results between the 3 groups,compared the index results of mild and severe acute pancreatitis and conducted correlation analysis.Results Serum amylase level,serum lipase level and C-reactive protein level in the study group were higher than that of the A2 group and A1 group,and the dif⁃ferences were statistically significant(all P<0.05);The serum amylase level of severe acute pancreatitis patients was(768.49±43.22)U/L,serum lipase level(1694.88±300.15)mg/L,C reactive protein level(137.49±13.35)mg/L,which were higher than(591.85±48.22)U/L,(1232.49±300.13)mg/L,(26.25±4.13)mg/L in patients with mild acute pancre⁃atitis,and the differences were statistically significant(t=19.288,7.702,56.288,all P<0.05).With the severity of acute pancreatitis,the serum amylase,serum lipase,and C-reactive protein increased significantly(r=0.128,0.139,0.137,all P<0.05).Conclusion During the early diagnosis of acute pancreatitis,serum amylase level,serum lipase level and C-reactive protein level can provide a certain basis for the successful diagnosis of the disease.It is found that with the severity of acute pancreatitis,the serum amylase level,serum lipase level and C-reactive protein level of the patients show a significant increase in the effective treatment of the disease can lay a foundation.
作者
刘瑜
LIU Yu(Department of Medical Laboratory,Tianshui First People's Hospital,Tianshui,Gansu Province,741000 China)
出处
《系统医学》
2024年第2期83-86,共4页
Systems Medicine
