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缩宫素联用卡前列素氨丁三醇治疗产后出血对产妇凝血指标、血栓弹力图指标的影响

Effects of Oxytocin Combined with Carprost Trobutrin in the Treatment of Postpartum Hemorrhage on Coagulation Index and Thromboelastogram Index of Parturients
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摘要 目的探讨缩宫素联用卡前列素氨丁三醇治疗产后出血对产妇凝血指标、血栓弹力图指标的影响。方法方便选取2021年1月—2022年12月厦门大学附属第一医院收治的84例产后出血产妇作为研究对象,根据随机数表法分为参照组和研究组,每组42例,参照组采取常规缩宫素治疗,研究组采取缩宫素联合卡前列素氨丁三醇治疗。比较两组临床治疗有效率、凝血相关指标、血栓弹力图指标。结果研究组临床治疗有效率95.24%高于参照组,差异有统计学意义(χ^(2)=6.145,P<0.05);治疗后,研究组产妇凝血活酶时间、凝血酶原时间均短于参照组,血清纤维蛋白原指标低于参照组,差异有统计学意义(P均<0.05)。结论对产后出血产妇实施缩宫素联用卡前列素氨丁三醇治疗,能取得更为理想的治疗效果,积极改善相关凝血指标和血栓弹力图指标。 Objective To explore the effect of oxytocin combined with carprost trobutrin on postpartum hemorrhage on coagulation index and thromboelastogram index of parturients.Methods A total of 84 women with postpartum hemor⁃rhage admitted to the First Affiliated Hospital of Xiamen University from January 2021 to December 2022 were conve⁃niently selected as the study objects.They were divided into the reference group and the study group according to the random number table method,with 42 cases in each group.The reference group was treated with conventional oxyto⁃cin,while the study group was treated with oxytocin combined with carprost tramine.The effective rate of clinical treat⁃ment,coagulation-related indexes and thromboelastogram indexes were compared between the two groups.Results The clinical effective rate of the study group was 95.24%higher than that of the reference group,the difference was statistically significant(χ^(2)=6.145,P<0.05).After treatment,the thromboplastin time and prothrombin time in the study group were shorter than those in the reference group,and the serum fibrinogen indexes were lower than those in the reference group,the differences were statistically significant(all P<0.05).Conclusion The combination of oxytocin and carprost trobutrin in the treatment of postpartum hemorrhage can achieve a better therapeutic effect,and actively improve the related coagulation index and thromboelastogram index.
作者 李晓东 郑艳辉 LI Xiaodong;ZHENG Yanhui(Department of Obstetrics and Gynecology,the First Affiliated Hospital of Xiamen University,Xiamen,Fujian Province,361000 China)
出处 《中外医疗》 2024年第1期4-7,共4页 China & Foreign Medical Treatment
基金 福建省自然科学基金(2021J05298)。
关键词 产后出血 缩宫素 卡前列素氨丁三醇 凝血指标 血栓弹力图指标 Postpartum hemorrhage Oxytocin Carprost trobutrin Coagulation index Thromboelastogram index
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