摘要
目的探讨非急性症状性颈内动脉闭塞(Internal Carotid Artery Occlusion,ICAO)患者血管内再通治疗失败的影响因素。方法方便选择2017年1月—2023年8月广西医科大学附属武鸣医院收治的54例非急性症状性ICAO患者作为研究对象,对患者进行血管内再通治疗,根据手术结果分为成功组(n=48)和未成功组(n=6),收集患者临床资料,分析患者血管内再通成功率、颈内动脉闭塞开通失败影响因素。结果非急性症状性颈内动脉闭塞患者血管内再通治疗成功率为88.89%,成功组高血压、冠心病、高脂血症比例低于未成功组,差异有统计学意义(P均<0.05),两组患者其余各项指标比较,差异无统计学意义(P均>0.05);Lo⁃gistic多因素回归分析显示:高血压、冠心病、高脂血症为颈内动脉闭塞开通失败独立危险因素(OR=1.328、1.521、1.234,P均<0.05)。结论血管内再通治疗非急性症状性ICAO,血管内再通成功率高,但高血压、冠心病、高脂血症因素也会对患者预后状况产生不良影响。因此,仍需进行长期随访,进一步观察血管内再通治疗的可行性和安全性。
Objective To explore the influential factors of failure of endovascular recanalization therapy in patients with non-acute symptomatic internal carotid artery occlusion.Methods 54 patients with non-acute symptomatic ICAO admitted to Wuming Hospital Affiliated to Guangxi Medical University from January 2017 to August 2023 were conveniently selected as the study subjects.Intravascular revascularization treatment was performed on the patients,who were divided into successful group(n=48)and unsuccessful group(n=6)according to the surgical results.Clinical data of the patients were collected.The factors affecting the success rate of intravascular recanalization and the opening failure of internal carotid artery occlusion were analyzed.Results The success rate of endovascular recanalization in patients with non-acute symptomatic internal carotid artery occlusion was 88.89%,the proportion of hypertension,coronary heart disease and hyperlipidemia in the successful group was lower than that in the unsuccessful group,the differences were statistically significant(all P<0.05),and there were no statistically significant differences in other indicators between the two groups(all P>0.05).Logistic multivariate regression analysis showed that hypertension,coronary heart disease and hyperlipidemia were independent risk factors for internal carotid artery occlusion failure(OR=1.328,1.521,1.234,all P<0.05).Conclusion Endovascular recanalization for non-acute symptomatic ICAO has a high success rate of endovascular recanalization,but the factors of hypertension,coronary heart disease,and hyperlipidemia also affect the prognostic status of patients.Therefore,long-term follow-up is still needed to further observe the feasibility and safety of endovascular recanalization treatment.
作者
韦英秀
崔伟
蒙喜斯
WEI Yingxiu;CUI Wei;MENG Xisi(Department of Neurology,Wuming Hospital Affiliated to Guangxi Medical University,Nanning,Guangxi Zhuang Autonomous Region,530199 China)
出处
《中外医疗》
2024年第2期66-69,共4页
China & Foreign Medical Treatment
关键词
非急性
症状性
颈内动脉闭塞
血管内再通治疗
可行性
安全性
Non-acute
Symptomatic
Internal carotid artery occlusion
Endovascular recanalization
Feasibility
Safety