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国产与进口23价肺炎球菌多糖疫苗接种后不良反应比较

Comparison of adverse reactions after vaccination with domestic and imported 23 valent pneumococcal polysaccharide vaccines
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摘要 目的评价国产与进口23价肺炎球菌多糖疫苗接种后的不良反应情况.方法收集滦平县疾控中心预防接种门诊2020年1月1日-2022年12月30日期间接种过23价肺炎球菌多糖疫苗的人群作为观察样本,其中接种国产疫苗782例,接种进口疫苗469例.结果所有接种人群接种后30min内均未出现局部和全身不良反应.72h内的局部反应以红肿、硬结、疼痛为主要症状,全身反应以发热、乏力、头痛为主要症状,未见严重全身不良反应.差异无统计学意义(χ^(2)=0.13,P>0.05).结论国产23价肺炎球菌多糖疫苗可以放心使用. Objective To evaluate the differences of adverse reactions between Domestic Huiyikang pneumococcal polysaccharide vaccinum and imported Newmofa Pneumovax 23 polysaccharide vaccinum.Methods Collecting the information of the people's vaccinations of Pneumovax 23 polysaccharide vaccinum at CDC Vaccination Clinic in Luanping from January 1st,2020 to December 30th,2022.Among these,there are 782 people who vaccine Domestic Huiyikang pneumococcal polysaccharide vaccinum and there are 469 people who vaccine imported Newmofa Pneumovax 23 polysaccharide vaccinum.Results All the people who vaccine these two kinds of vaccinums haven't appeared neither the local adverse reactions nor systemic adverse reactions in 30min.And in 72h,the main local reactions are in form of redness and swelling,induration and pain.And the main systemic reactions are in form of high fever,tiredness,and headache.There is no example of serious systemic reactions.And these two kinds of vaccinus are not statistically significant.(χ^(2)=0.13,P>0.05).Conclusion Domestic Huiyikang pneumococcal polysaccharide vaccinum can be used with confidence.
作者 王桂红 康素伶 周艳洁 Wang Guihong;Kang Suling;Zhou Yanjie(Market Supervision Administration of Luanping County,Chengde,Hebei 068250,China;Disease Prevention and Control Center of Luanping County,Chengde,Hebei 068250,China)
出处 《首都食品与医药》 2024年第6期85-86,共2页 Capital Food Medicine
关键词 肺炎 安全性 23价肺炎球菌多糖疫苗 不良反应 Pneumonia Safety 23-valent pneumococcal polysaccharide vaccine Adverse reactions
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