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基弧区非球面设计角膜塑形镜对近视青少年角膜屈光度、角膜内皮及眼轴增长的影响

Effect of base curve aspheric orthokeratology lens on corneal refraction,corneal endothelium and axial length elongation of myopic adolescents
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摘要 目的:探讨基弧区非球面设计角膜塑形镜对近视青少年角膜屈光度、角膜内皮及眼轴增长的影响。方法:回顾性分析98例近视(-1.00 D~-3.50 D)患者的病历资料。根据所选基弧区设计的不同角膜塑形镜分为两组,基弧区球面设计为S组(n=50);基弧区非球面设计为A组(n=48)。比较两组患者戴镜前及配戴3个月后角膜地形图上角膜4个轴方向及顶点处角膜的屈光力值、角膜相对屈光力,戴镜前及1年后角膜内皮相关系数与眼轴。结果:S组除T1、S1、I1.5,A组除I1外其余各点位角膜相对屈光力均发生变化(P<0.05),两组戴后角膜相对屈光力由戴前的负屈光力朝正屈光力方向改变。戴镜后两组在角膜直径3 mm内的各点位上比较有统计学差异(P<0.05)。1年后S组眼轴增长(0.31±0.20)mm,A组增长(0.20±0.19)mm,两组比较有统计学差异(P<0.05)。结论:近视青少年佩戴基弧区非球面设计角膜塑形镜后角膜相对屈光力朝正屈光力方向改变,在角膜直径3 mm内表现出更明显的非球面治疗区,眼轴增长更慢,对角膜内皮相关指数无影响。 Objective:To explore the effect of base curve aspheric orthokeratology lens on corneal refraction,corneal endothelium and axial length elongation of myopic adolescents.Methods:Retrospective analysis of medical records of 98 patients with myopia(-1.00D~-3.50D).The subjects were divided into S group(n=50,base curve spherical orthokeratology lens)and A group(n=48,base curve aspheric orthokeratology lens)according to the lenses they chose.The two groups were compared in terms of refractive power values and relative corneal refractive power in 4 corneal axis directions and at the corneal apex on corneal topography before wearing lenses and after wearing the lenses for 3 months,corneal endothelium related parameters and axial length before wearing the lenses and after wearing the lenses for 1 year.Results:Except for T1,S1,I1.5 in S group and I1 in A group,the relative corneal refractive power at the other points changed(P<0.05).The relative corneal refractive power of the two groups changed from negative refractive power before wearing the lenses to positive refractive power.After wearing the lenses,there were significant differences between the two groups in each point within 3 mm of the corneal diameter.A year later,axial length of S group increased by 0.31±0.20mm,and that of A group increased by 0.20±0.19 mm,there was statistical difference between the two groups(P<0.05).Conclusion:The relative corneal refractive power of myopic adolescents changes to positive refractive power after wearing base curve aspheric orthokeratology lenses.Besides,they have more obvious aspheric treatment area within 3 mm of the corneal diameter,and axial growth becomes slower,without influence on corneal endothelium-related parameters.
作者 王琼 王瑞 林江 周仕萍 毛馨遥 WANG Qiong;WANG Rui;LIN Jiang;ZHOU Shi-ping;MAO Xin-yao(Department of Strabismus and Pediatric Ophthalmology,Chengdu Aier Eye Hospital,Chengdu 610000,Sichuan,China)
出处 《川北医学院学报》 CAS 2024年第3期379-383,共5页 Journal of North Sichuan Medical College
基金 四川省成都市医学科研项目(2022341)。
关键词 近视 青少年 角膜塑形镜 基弧区非球面设计 角膜屈光度 Myopia Adolescent Orthokeratology lens Base curve aspheric design Corneal refraction
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