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宫颈双球囊在晚期妊娠促宫颈成熟中的临床应用

Clinical Application of Cervical Double Balloon in Promoting Cervical Maturation in Late Pregnancy
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摘要 目的探讨晚期妊娠促宫颈成熟中宫颈双球囊的临床应用。方法回顾性选取2022年8月至2023年8月本院收治的晚期妊娠孕妇120例,依据促宫颈成熟方法分为宫颈双球囊组、普贝生(地诺前列酮栓)栓剂组两组,各60例。统计分析两组宫颈成熟度、心理状态、临床疗效、临产发动时间、临产至分娩时间、产后出血量、分娩方式、产后2 h出血量、新生儿Apgar评分、不良妊娠结局发生情况、不良反应发生情况。结果宫颈双球囊组孕妇的宫颈Bishop评分高于普贝生栓剂组(P<0.05),焦虑评分、抑郁评分均低于普贝生栓剂组(P<0.05)。宫颈双球囊组孕妇的总有效率96.67%(58/60)高于普贝生栓剂组66.67%(40/60)(χ^(2)=18.033,P<0.05)。宫颈双球囊组孕妇的临产发动时间、临产至分娩时间均短于普贝生栓剂组(P<0.05),产后出血量少于普贝生栓剂组(P<0.05)。宫颈双球囊组孕妇的分娩方式阴道分娩率高于普贝生栓剂组,剖宫产率低于普贝生栓剂组(χ^(2)=13.889,P<0.05)。宫颈双球囊组产后2 h出血量<500 ml比例高于普贝生栓剂组,≥500 ml比例低于普贝生栓剂组(χ^(2)=4.615,P<0.05)。宫颈双球囊组孕妇的新生儿Apgar评分0~3分、4~7分比例均低于普贝生栓剂组,8~10分比例高于普贝生栓剂组(Z=1.976,P<0.05)。宫颈双球囊组孕妇的不良妊娠结局发生率6.67%(4/60)低于普贝生栓剂组23.33%(14/60)(χ^(2)=6.536,P<0.05)。宫颈双球囊组孕妇的不良反应发生率3.33%(2/60)低于普贝生栓剂组25.00%(15/60)(χ^(2)=11.582,P<0.05)。结论晚期妊娠促宫颈成熟中宫颈双球囊的临床应用效果较普贝生栓剂好。 Objective To explore the clinical application of cervical double balloon in promoting cervical maturation during late pregnancy.Methods A retrospective study was conducted on 120 late pregnancy pregnant women from August 2022 to August 2023 in our hospital.They were divided into two groups based on cervical ripening promotion methods:cervical double balloon group and Pubesheng suppository group,with 60 cases in each group.The cervical maturity,psychological status,clinical efficacy,onset time of labor,time from labor to delivery,postpartum bleeding volume,delivery method,2-hour postpartum bleeding volume,neonatal Apgar scores,incidences of adverse pregnancy outcomes,and incidences of adverse reactions between two groups were statistically analyzed.Results The cervical Bishop score of the cervical double balloon group was higher than that in the Pubesheng suppository group(P<0.05),while the anxiety and depression scores were lower than those in the Pubesheng suppository group(P<0.05).The total effective rate of the cervical double balloon group was 96.67%(58/60)higher than that in the Pubesheng suppository group,which was 66.67%(40/60)(χ^(2)=18.033,P<0.05).The onset time and delivery to delivery time of the cervical double balloon group were shorter than those of the Pubesheng suppository group(P<0.05),and the postpartum bleeding volume was lower than that of the Pubesheng suppository group(P<0.05).The vaginal delivery rate of the cervical double balloon group was higher than that of the Pubesheng suppository group,and the cesarean section rate was lower than that of the Pubesheng suppository group(χ^(2)=13.889,P<0.05).The proportion of postpartum bleeding<500 ml in the cervical double balloon group was higher than that in the Pubesheng suppository group,and the proportion of bleeding≥500 ml was lower than that in the Pubesheng suppository group(χ^(2)=4.615,P<0.05).The Apgar scores of newborns in the cervical double balloon group were lower at 0-3 points and 4-7 points compared to the Pubesheng suppository group,while the proportion of 8-10 points was higher than the Pubesheng suppository group(Z=1.976,P<0.05).The incidence of adverse pregnancy outcomes in the cervical double balloon group was 6.67%(4/60)lower than 23.33%(14/60)in the Pubesheng suppository group(χ^(2)=6.536,P<0.05).The incidence of adverse reactions in the cervical double balloon group was 3.33%(2/60)lower than 25.00%(15/60)in the Pubesheng suppository group(χ^(2)=11.582,P<0.05).Conclusion The clinical application effect of cervical double balloon therapy in promoting cervical maturation in late pregnancy is better than that of Pubesheng suppositories.
作者 关雪梅 陶艳琴 GUAN Xuemei;TAO Yanqin(The First People's Hospital of Jiayuguan City,Gansu Province,Jiayuguan 735100,China)
出处 《中国医药指南》 2024年第9期1-4,共4页 Guide of China Medicine
基金 甘肃省嘉峪关市科技计划资助(项目编号23-31)。
关键词 晚期妊娠 促宫颈成熟 普贝生栓剂 宫颈双球囊 不良妊娠结局 不良反应 Late pregnancy Promoting cervical maturation Pubesheng suppository Cervical double balloon Adverse pregnancy outcomes Adverse reactions
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