摘要
目的探讨经颅磁刺激联合高压氧治疗脑外伤后抑郁患者的临床疗效。方法本研究对象为2020年5月~2022年9月85例脑外伤后抑郁患者,根据患者治疗意愿设为对照组与观察组。对照组45例采用常规治疗,观察组40例在对照组治疗基础上给予经颅磁刺激联合高压氧治疗。治疗前后评估美国国立卫生院神经功能缺损评分(NHISS)、生活能力量表(ADL)、汉密尔顿焦虑、抑郁量表(HAMA)、(HAMD)。结果治疗后两组患者NHISS评分显著下降,ADL评分显著升高,且观察组治疗后NHISS评分较对照组低,ADL评分均较对照组高,(P<0.05);治疗后两组患者HAMD评分、HAMA评分均显著下降,且观察组治疗后各项评分均较对照组低,(P<0.05)。结论经颅磁刺激联合高压氧治疗脑外伤后抑郁既能改善患者神经功能以及活动能力,还能降低患者焦虑抑郁情绪。
Objective To investigate the clinical efficacy of transcranial magnetic stimulation combined with hy-perbaric oxygen in the treatment of patients with depression after traumatic brain injury.Methods Eighty-five patients with depression after traumatic brain injury from May 2020 to September 2022 were the subjects of this study,which were set up as control group and observation group according to the patients'wishes.Forty-five cases in the control group were treated with conventional treatment,and 40 cases in the observation group were given transcranial magnetic stimulation combined with hyperbaric oxygen therapy on the basis of treatment in the control group.The National Insti-tutes of Health Neurological Impairment Score(NHISS),the Ability to Live Scale(ADL),the Hamilton Anxiety and Depression Inventory(HAMA),and(HAMD)were assessed before and after treatment.Results HAMD scores and HAMA scores decreased significantly in both groups after treatment,and all scores were lower in the observation group than in the control group after treatment(P<0.05).The NHISS score decreased significantly and the ADL score in-creased significantly in both groups after treatment,and the NHISS score was lower and the ADL score was higher in the observation group than in the control group after treatment(P<0.05).Conclusion Transcranial magnetic stimulation combined with hyperbaric oxygen therapy for post-traumatic brain injury depression can improve neurological function and mobility as well as reduce anxiety and depression in patients.
作者
申利坊
方明珠
闫莹莹
SHEN Lifang;FANG Mingzhu;YAN Yingying(Zhengzhou University Fifth Affiliated Hospital,Zhengzhou 450052,China)
出处
《国际精神病学杂志》
2024年第1期208-210,共3页
Journal Of International Psychiatry
基金
河南省医学科技攻关计划联合共建项目(编号:LHGJ20220565)。
关键词
经颅磁刺激
高压氧
脑外伤后抑郁
神经功能
Transcranial magnetic stimulation
Hyperbaric oxygen
Post-traumatic brain injury Depression
Neurological function
