摘要
目的 通过分析食管鳞状细胞癌的临床和组织病理学特点,了解影响食管鳞状细胞癌患者术后预后的影响因素。方法 采用病例回顾的调查方法登录医院病案管理系统,调阅病案,以病案信息为依据,收集2011年1月—2015年12月期间在某三甲医院收治的721例食管癌患者。根据病例纳入标准,对306例食管鳞状细胞癌术后患者进行随访,共得到有效随访261例,分析生存状况及预后影响因素。结果 本研究261例食管鳞癌术后患者,直至随访截止日期,结局死亡144例(55.17%);生存时间0~84个月,中位生存时间33.00月,平均生存时间36.55月。食管鳞状细胞癌术后预后单因素分析结果显示:年龄、治疗方式、定期复查、淋巴结转移率、TNM分期、病理形态、血红蛋白和血清白蛋白对预后有影响(P<0.05)。多因素分析结果显示年龄、治疗方式、TNM分期和病理形态影响食管鳞状细胞癌术后预后。结论 食管鳞状细胞癌术后生存的影响因素为:年龄、治疗方式、TNM分期和病理形态。年龄越小、进行化疗、病理形态未分化、TNM分期越小的患者具有更长的生存时间。
Objective To analyze the clinical and histopathological characteristics of esophageal squamous cell carcinoma(ESCC)and understand the influence factors of postoperative prognosis of patients with esophageal squamous cell carcinoma.Methods Case review survey method was used to log in the hospital medical record management system,access medical records,and use medical record information as the basis.721 cases of esophageal cancer patients admitted to the hospital from January 2011 to December 2015 were collected.According to the case selection criteria,306 patients with esophageal squamous cell carcinoma were followed up and 261 cases’survival status and prognostic factors were analyzed.Results In the 261 cases,up to the follow-up deadline 144 cases(55.17%)died;the survival time was 0~84 months,the median survival time was 33.00 months and the average survival time was 36.55 months.The results of single factor analysis showed that age,treatment method,periodic review,metastatic lymph node ratio,TNM staging,pathological morphology,hemoglobin and serum albumin affect the postoperative prognosis of esophageal squamous cell carcinoma(P<0.05).Conclusion The influencing factors for postoperative survival of esophageal squamous cell carcinoma patients include age,treatment method,TNM staging,and pathological morphology.Patients who are younger,undergo chemotherapy,have undifferentiated pathological morphology and have a smaller TNM stage have longer survival time.
作者
韩冰
赵晶
HAN Bing;ZHAO Jing(Heze Medical College,Heze 274000,Shandong)
出处
《菏泽医学专科学校学报》
2024年第1期44-49,共6页
Journal of Heze Medical College
关键词
食管鳞状细胞癌
生存状况
预后
影响因素
Esophageal squamous cell carcinoma
Survival status
Prognosis
Influence factor
