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中药复方抗呼吸道病毒性疾病研究进展

Research progress of Traditional Chinese Medicine compound against respiratory viral diseases
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摘要 近年来,据不完全统计,由病原微生物引起的所有呼吸道疾病中,由病毒导致的急性呼吸道感染约占80%,是目前世界范围内发病率最高的疾病。呼吸道病毒,如严重急性呼吸系统综合征冠状病毒(SARS-CoV)、SARS-CoV-2,甲型流感病毒和呼吸道合胞病毒等,对社会公共卫生安全构成较大威胁,目前,还没有开发出特效药。由于中药具有多组分多靶点的协同作用,在呼吸道病毒疾病的预防、治疗康复和保健方面具有独特的优势,近年来,许多临床医生和研究人员从不同层面对中药治疗呼吸道病毒疾病进行了一系列研究和探索,对中医药的临床疗效和治疗机制有了更清晰的认识。本文通过综述中医药治疗呼吸道病毒疾病的临床疗效研究和作用机制,为中医药更好治疗呼吸道病毒疾病提供有力的证据,以期推动中医药的发展及其在呼吸道病毒疾病方面的潜在应用。 In recent years,according to incomplete statistics,acute respiratory infections caused by viruses account for approximately 80%of all respiratory diseases triggered by pathogenic microorganisms,making these the diseases with the highest incidence rates worldwide.Respiratory viruses,such as the Severe Acute Respiratory Syndrome Coronavirus(SARS-CoV),SARS-CoV-2,influenza A virus and respiratory syncytial virus,pose a threat to public health,yet no specific drugs have been developed to combat these viruses effectively.Due to its synergistic multi-component and multi-target actions,Traditional Chinese Medicine(TCM)has unique advantages in the prevention,treatment,and rehabilitation of respiratory viral diseases.In recent years,many clinicians and researchers have conducted extensive studies and explorations into the use of TCM for treating respiratory viral diseases,leading to a clearer understanding of its clinical efficacy and therapeutic mechanisms.This article reviews the clinical efficacy and mechanisms of action of TCM in treating respiratory viral diseases,providing strong evidence for its enhanced treatment capabilities and promoting the development and potential application of TCM in the field of respiratory viral diseases.
作者 马旺明 李玮婕 王萍 李兵 许海玉 Ma Wangming;Li Weijie;Wang Ping;Li Bing;Xu Haiyu(Jiangxi University of Chinese Medicine,Nanchang 330004,Jiangxi,China;Institute of Chinese Materia Medica,China Academy of Chinese Medical Sciences,Beijing 100700,China;Key Laboratory for Research and Evaluation of Traditional Chinese Medicine,National Medical Products Administration,China Academy of Chinese Medical Sciences,Beijing 100700,China)
出处 《生物医学转化》 2024年第1期37-47,共11页 Biomedical transformation
基金 国家重点研发计划项目(2023YFC2308200,2022YFE0119300,2023YFC3502900) 国家自然科学基金项目(82204711,82304830) 名贵中药资源可持续利用能力建设项目(2060302)。
关键词 呼吸道病毒 流感病毒 冠状病毒 中药复方 临床疗效与评价 作用机制 Respiratory viruses Influenza viruses Coronaviruses Traditional Chinese Medicine compound Clinical efficacy and evaluation Mechanism of action
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