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基于累积缺陷原则构建的衰弱指数及其应用

Frailty index model based on the principle of cumulative defects and its application
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摘要 衰弱是因机体生理储备和应激适应能力下降和失调而易发生不良结局的临床状态或综合征。目前,关于衰弱的评估方法尚无金标准,但有研究发现基于累积缺陷原则构建的衰弱指数模型对各种不良临床事件的预测能力高于其他衰弱评估方法。本文主要对基于累积缺陷原则构建的衰弱指数及其构建方法、常见种类及其应用等方面的相关研究进行综述,为衰弱评估提供新思路和新方法。 Frailty is a clinical state or syndrome that predispose the patients to adverse health outcomes due to the decline of physiological reserve and stress adaptability.No gold standard is available for the assessment of frailty,but the cumulative defect model has been found to be better at predicting various adverse clinical events than other frailty assessment methods.This paper reviews the relevant research in the frailty index based on the principle of cumulative defects and the approaches to its construction,common types and applications to provide new insights into and tools for frailty evaluation.
作者 任燕 杨永学 陈善萍 郑晓梅 严雪丹 周莉华 Ren Yan;Yang Yongxue;Chen Shanping;Zheng Xiaomei;Yan Xuedan;Zhou Lihua(Department of Gerontology and Geriatrics,Geriatric Diseases Institute of Chengdu,Cancer Prevention and Treatment Institute of Chengdu,Chengdu Fifth People′s Hospital,The Second Clinical Medical College,Affiliated Fifth People′s Hospital of Chengdu University of Traditional Chinese Medicine,Chengdu 611137,China)
出处 《中华老年多器官疾病杂志》 2024年第3期229-232,共4页 Chinese Journal of Multiple Organ Diseases in the Elderly
基金 四川省医学会课题项目(Q19036) 成都市科技局项目(2022251)。
关键词 老年人 衰弱 衰弱指数 累积缺陷 衰弱评估工具 aged frailty frailty index cumulative defects frailty assessment tool
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