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150例围绝经期综合征患者用药依从性调查与分析

Investigation and Analysis of Medication Compliance in 150 Patients with Perimenopausal Syndrome
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摘要 目的:调查围绝经期综合征患者的用药依从性,分析用药依从性的影响因素,为围绝经期综合征患者的用药管理提供参考。方法:选取2023年2—4月于四川大学华西第二医院更年期门诊复诊的围绝经期综合征患者开展用药情况问卷调查,采用Morisky量表调查用药依从性,通过二元Logistic回归模型分析用药依从性的影响因素。结果:共发出调查问卷151份,有效回收150份(回收率为99.34%)。150例调查对象中,70.00%的调查对象(105例)重视该疾病,但69.33%的调查对象(104例)尚不了解围绝经期综合征,74.67%的调查对象(112例)对使用药物治疗疾病的重要性了解不足,且50.00%的调查对象(75例)对不听从医嘱服药危害性的了解程度不足。150例调查对象中,用药治疗依从性好的有54例(占36.00%),用药依从性差的有96例(64.00%)。单因素分析结果显示,围绝经期综合征患者的用药依从性与在职情况、文化程度、居住地、个人月收入、婚姻状况、是否已绝经、是否了解药物治疗的重要性、是否了解不按医嘱服药的危害性有关(P<0.05);二元Logistic回归分析结果显示,导致患者用药依从性差的危险因素有个人月收入<10000元、单身、未绝经、不了解药物治疗的重要性(P<0.05)。患者认为医院提供疾病科普健康知识、个体化用药教育或在线用药提醒等可提高用药依从性。结论:围绝经期综合征患者总体用药依从性不高,用药依从性受经济因素、家庭环境、对疾病和药物的认知水平等因素影响,建议医院开展围绝经期健康知识科普、个性化用药教育、在线用药提醒等,以提高患者用药依从性。 OBJECTIVE:To investigate the medication compliance in patients with perimenopausal syndrome,analyze the influencing factors of medication compliance,so as to provide reference for medication management of patients with perimenopausal syndrome.METHODS:A questionnaire survey was performed in patients with perimenopausal syndrome revisited in the menopause clinic of West China Second Hospital,Sichuan University from Feb.to Apr.2023.Morisky scale was used to investigate medication compliance,and the risk factors affecting medication compliance were analyzed by binary Logistic regression model.RESULTS:A total of 151 questionnaires were sent out and 150 were effectively recovered(recovery rate was 99.34%).Of 150 respondents,70.00%(105 cases)took the disease seriously,yet 69.33%(104 cases)did not understand perimenopausal syndrome,74.67%(112 cases)did not know enough about the importance of using medication to treat the disease,and 50.00%(75 cases)did not know enough about the dangers of not following the instructions.Of 150 respondents,54 patients(36.00%)had good medication compliance and 96 patients(64.00%)had poor medication compliance.Univariate analysis showed that medication compliance of patients with perimenopausal syndrome was related to on-the-job status,education level,residence,monthly income,marital status,postmenopausal status,understanding of the importance of medication,and understanding of the harm of not taking medication as prescribed(P<0.05).Binary Logistic regression analysis showed that the risk factors leading to poor medication compliance were monthly personal income<10000 yuan,single,pre-menopausal,and not understanding the importance of medication(P<0.05).Patients believed that providing health knowledge of disease popularization,individualized medication education or online medication reminder in hospitals could improve medication compliance.CONCLUSIONS:The overall medication compliance of patients with perimenopausal syndrome is not high,and medication compliance is affected by economic factors,family environment,disease and drug cognition level.It is suggested that hospitals should carry out health knowledge popularization,individualized medication education and online medication reminder to improve medication compliance of patients.
作者 张建华 康冰瑶 陈任译 冯娟 李丹 ZHANG Jianhua;KANG Bingyao;CHEN Renyi;FENG Juan;LI Dan(Nursing Unit of Pediatric Outpatient,West China Second University Hospital,Sichuan University,Chengdu 610041,China;Key Laboratory of Birth Defects and Related Diseases of Women and Children,Sichuan University,Ministry of Education,Chengdu 610041,China;Nursing Unit of Gynaecology,West China Second University Hospital,Sichuan University,Chengdu 610041,China)
出处 《中国医院用药评价与分析》 2024年第3期362-366,共5页 Evaluation and Analysis of Drug-use in Hospitals of China
基金 四川省干部保健科研项目(普及应用项目)(No.川干研2022-1702)。
关键词 围绝经期综合征 用药调查 用药依从性 Perimenopause syndrome Medication investigation Medication compliance
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