摘要
目的了解动物药材的研究现状、热点和趋势,为后续研究提供参考。方法检索中国知识资源总库(CNKI)、中文科技期刊数据库(VIP)、中国学术期刊数据库(万方数据)、中国生物医学文献数据库(CBM)2000年1月1日-2023年4月30日收录的动物药材相关研究文献。采用NoteExpress3.6合并去重,采用CiteSpace6.1.R6软件绘制作者、机构、关键词知识图谱并进行解读。结果共纳入1169篇文献,该领域发文量整体呈平稳波动趋势;主要来源期刊有《时珍国医国药》《中国中药杂志》《中国现代中药》等;主要研究机构有中国中医科学院、长春中医药大学、中国医学科学院等;涉及676位作者,发文较多的有张辉(22篇)、刘睿(15篇)、林喆和马双成(均为14篇)等;高频关键词有“鉴别”“中药资源”“临床应用”等。结论动物药材资源调查、药用动物规范化养殖、珍稀药用动物资源替代品开发、动物药材质量标准体系构建为该领域研究热点;基于蛋白质组学、多肽组学、转录组学整合分析策略的动物药材药效物质基础研究,且从分子生物学水平揭示动物药材的信号通路和作用靶点为该领域研究趋势。
Objective To understand the research status,hotspots and trends of animal medicinal materials;To provide reference for future research.Methods The literature related to animal medicinal materials was retrieved from CNKI,VIP,Wanfang Data and CBM from January 1,2000 to April 30,2023.NoteExpress 3.6 was used to merge and deduplicate,and the author,institution and keywords were mapped and interpreted by CiteSpace 6.1.R6 software.Results A total of 1169 articles were included,and the overall publication quantity in this field showed a stable fluctuation trend;the top journals were Lishizhen Medicine and Materia Medica Research,China Journal of Chinese Materia Medica and Modern Chinese Medicine;the main research institutions were China Academy of Chinese Medical Sciences,Changchun University of Chinese Medicine and Chinese Academy of Medical Sciences;a total of 676 authors were involved,and the authors with more publications included Zhang Hui(22),Liu Rui(15),Lin Zhe and Ma Shuangcheng(14);high-frequency keywords included“identification”,“TCM resources”,“clinical application”and so on.Conclusion Resource survey of animal medicinal materials,standardized breeding of medicinal animals,development of alternatives to rare medicinal animal resources,and construction of quality standard system for animal medicinal materials are the research hotspots in this field.The basic research of pharmacodynamic substances of animal medicinal materials based on the integrated analysis strategies of proteomics,peptideomics and transcriptomics,and the revelation of the signaling pathways and targets of animal medicinal materials from the molecular biology level are the research trends in this field.
作者
夏青青
陈偶英
曾勇
王金星
康焱红
方芳
陈燕
李东雅
朱海利
XIA Qingqing;CHEN Ouying;ZENG Yong;WANG Jinxing;KANG Yanhong;FANG Fang;CHEN Yan;LI Dongya;ZHU Haili(Hunan University of Chinese Medicine,Changsha 410208,China;The First Hospital of Hunan University of Chinese Medicine,Changsha 410007,China;Hunan Academy of Traditional Chinese Medicine,Changsha 410006,China;Hunan Academy of Traditional Chinese Medicine Affiliated Hospital,Changsha 410006,China)
出处
《中国中医药信息杂志》
CAS
CSCD
2024年第4期72-78,共7页
Chinese Journal of Information on Traditional Chinese Medicine
基金
国家自然科学基金(82104842)
湖南省中医药科研计划项目(202293)
湖南省教育厅科学研究重点项目(22A0268)。
