摘要
目的调查研究机采血小板献血者血液初筛不合格的原因。方法将驻马店市中心血站2022年6月至2022年12月480例机采血小板献血者作为研究对象。在单采血小板献血前,所有献血者均采集肘静脉血4 m L并进行血样初筛,依据《血站技术规程2019版》确定血液筛查结果,统计480例机采血小板献血者血液初筛结果与初筛不合格项目;另外对比男性、女性初筛不合格项目。结果共计筛查480例,其中共40例出现血液初筛不合格,初筛不合格率为8.33%;机采血小板献血者血液初筛不合格项目中,丙氨酸转氨酶(ALT)检测值>50 U/L占比为17.50%、血小板计数检测值<150×10^(9)/L占比为25.00%、血细胞比容(HCT)检测值<0.36占比为25.00%、血红蛋白(Hb)检测值不合格占比为2.50%、白细胞计数(WBC)检测值不合格占比为15.00%、乳糜血不合格占比为12.50%、乙型肝炎病毒表面抗原(HBs Ag)阳性占比为2.50%;男性、女性机采血小板献血者血液初筛不合格项目中ALT检测值>50 U/L、Hb检测值不合格率对比差异有统计学意义(P<0.05),其余对比差异无统计学意义(P>0.05)。结论机采血小板献血者血液初筛不合格的项目主要包括ALT检测值>50 U/L、血小板计数检测值<150×10^(9)/L、HCT检测值<0.36占比最高,男性初筛不合格项目主要以ALT检测值>50 U/L为主,女性则主要以Hb检测值不合格为主。
Objective To investigate the reasons for the failure of blood primary screening in mechanically collected platelet donors.Methods A total of 480 mechanically collected platelet donors from the central blood station of Zhumadian from June 2022 to December 2022 were selected as the study subjects.Before donating single platelet samples,all donors collected 4 ml of elbow vein blood and underwent initial blood sample screening.The blood screening results were determined according to the 2019 edition of the Blood Station Technical Regulations,and 480 mechanically collected platelet donors were counted for their initial blood screening results and items that did not pass the initial screening;Additionally,the items that did not pass the initial screening between males and females were compared.Results A total of 480 cases were screened,of which 40 cases were found to have failed the initial blood screening,with a failure rate of 8.33%;In the initial screening of mechanically collected platelet donors,17.50%were found to have an alanine aminotransferase(ALT)detection value>50 U/L,25.00%were found to have a platelet count detection value<150×10^(9)/L,25.00%were found to have a hematocrit(HCT)detection value<0.36,2.50%were found to have a hemoglobin(Hb)detection value unqualified,15.00%were found to have a white blood cell count(WBC)detection value unqualified,12.50%were found to have a chyle blood count detection value unqualified,and 2.50%were found to be positive for hepatitis B virus surface antigen(HBsAg);There was a statistically significant difference(P<0.05)in the unqualified rate of ALT detection value>50 U/L and Hb detection value between male and female mechanically collected platelet donors in the initial screening of blood,while there was no statistically significant difference(P>0.05)in the other comparisons.Conclusion The items that do not pass the initial screening of blood donors for machine collected platelets mainly include ALT test values>50 U/L,platelet count test values<150×10^(9)/L,and HCT test values<0.36,with the highest proportion.The main items that do not pass the initial screening for males are ALT test values>50 U/L,and for females,Hb test values are mainly unqualified.
作者
王爱辉
刘彬
邵漫
WANG Aihui;LIU Bin;SHAO Man(Collection Department,Zhumadian Central Blood Station,Zhumadian Henan 463000,China)
出处
《临床研究》
2024年第4期44-46,共3页
Clinical Research
关键词
机采血小板献血者
血液初筛
不合格的原因
machine collected platelet donors
primary blood screening
reasons for non-compliance
