摘要
【目的】探讨三维超声评估妊娠期糖尿病(GDM)患者孕晚期胎盘血流参数的价值。【方法】回顾性分析2021年1月至12月本院收治的100例GDM孕晚期孕妇的临床资料,将其设为观察组;另选取同期在本院定期产检的100例正常孕妇作为对照组。两组均采用三维多普勒超声检查胎盘内血管状态,观察胎儿宫内发育状况。比较两组胎盘血流参数[血管化指数(VI)、血流指数(FI)、血流/血管比值(VFI)];采用Spearman秩相关分析GDM患者孕晚期血糖指标与胎盘血流参数的相关性;比较两组新生儿情况和阿普加评分(Apgar);比较两组孕妇妊娠结局。【结果】观察组VI、FI、VFI均低于对照组(P<0.05);相关性分析显示:GDM患者孕晚期血糖指标与VI、FI、VFI呈负相关(P<0.05);观察组胎儿窘迫、巨大儿、宫内生长受限(FGR)占比高于对照组(P<0.05),Apgar评分低于对照组(P<0.05);观察组不良妊娠结局占比高于对照组。【结论】三维超声可准确反映胎盘血流参数,且胎盘血流参数与GDM密切相关,临床可将其用于预测妊娠结局以及围生儿状态,为临床尽早制定应对措施提供依据。
【Objective】To explore the value of three-dimensional ultrasound in evaluating placental blood flow parameters in patients with gestational diabetes mellitus(GDM)in the third trimester.【Methods】The clinical data of 100 pregnant women with GDM in the third trimester admitted to our hospital from January to December 2021 were retrospectively analyzed,and they were set as the observation group;In addition,100 normal pregnant women who underwent regular prenatal examination in our hospital during the same period were selected as the control group.Three dimensional Doppler ultrasound was used to examine the placental vascular status and observe the fetal intrauterine development in both groups.The placental blood flow parameters[vascularization index(VI),blood flow index(FI),blood flow/vascular ratio(VFI)]were compared between the two groups;Spearman rank correlation was used to analyze the correlation between blood glucose and placental blood flow parameters in the third trimester of GDM patients;The neonatal condition and Apgar score were compared between the two groups;The pregnancy outcomes of the two groups were compared.【Results】The levels of VI,FI and VFI in the observation group were lower than those in the control group(P<0.05);The correlation analysis showed that the blood glucose index in the third trimester of GDM patients was negatively correlated with VI,FI and VFI(P<0.05);The proportion of fetal distress,macrosomia and intrauterine growth restriction(FGR)in the observation group was higher than that in the control group(P<0.05),and the Apgar score was lower than that in the control group(P<0.05);The proportion of adverse pregnancy outcomes in the observation group was higher than that in the control group.【Conclusion】Three dimensional ultrasound can accurately reflect the placental blood flow parameters,and the placental blood flow parameters are closely related to GDM.It can be used to predict the pregnancy outcome and perinatal status in clinic,and provide the basis for clinical early development of countermeasures.
作者
李燕
齐明
LI Yan;QI Ming(Department of Ultrasound Diagnosis,Hanzhong Central Hospital,Hanzhong Shaanxi 723000)
出处
《医学临床研究》
CAS
2024年第3期403-405,409,共4页
Journal of Clinical Research
关键词
糖尿病
妊娠
超声检查
产前
胎盘
血流动力学
Diabetes,Gestational
Ultrasonography,Prenatal
Placenta
Hemodynamics
